Adrien Crestani1, Claire Theodore2, Jean-Marc Levaillant2, Isabelle Thomassin-Naggara3,4, Dounia Skalli2, GrÉgoire Miaihle2, Yohann Dabi2, Bassam Haddad2, Cyril Touboul2,5. 1. Department of Obstetrics and Gynaecology and Reproductive Médecine, Centre Hospitalier Intercommunal de Créteil, Créteil, France adriencrestani@hotmail.fr. 2. Department of Obstetrics and Gynaecology and Reproductive Médecine, Centre Hospitalier Intercommunal de Créteil, Créteil, France. 3. Service de Radiologie, Centre Hospitalier Intercommunal de Créteil, Créteil, France. 4. Service de Radiologie, Hôpital Tenon, Sorbonne Université, Paris, France. 5. INSERM UMR S 938: Biologie et Thérapie des Cancers, Centre de Recherches Saint-Antoine-CRSA, Paris, France.
Abstract
BACKGROUND/AIM: Magnetic resonance (MR) and ultrasound (US) fusion imaging (MR-US fusion) is already used to guide prostate biopsies and has been proven accurate for diagnosing cervical cancer. In this study, we aimed to evaluate the feasibility and performance of MR-US fusion for characterizing adnexal masses. PATIENTS AND METHODS: A retrospective study was conducted between 2014 and 2018 including women referred to our Gynaecological Oncology Department for characterization of an adnexal mass (n=106). Performance of MR-US fusion was evaluated in a subgroup of patients who underwent surgery (n=26). Two readers, blinded to final histology, performed and rated US findings according to the International Ovarian Tumor Analysis simple rules score, MR according to Ovarian-Adnexal Reporting Data System Magnetic score, and MR-US fusion through a tailored score. The reference outcome was the final pathology. RESULTS: MR-US fusion had a sensitivity of 100% (95%CI=80-100), specificity of 89% (95%CI=52-99), positive likelihood ratio of 9 (95%CI=1.4-57), and accuracy of 96% (95%CI=80-99). CONCLUSION: MR-US fusion is feasible for characterizing adnexal masses to predict ovarian cancer. Copyright
BACKGROUND/AIM: Magnetic resonance (MR) and ultrasound (US) fusion imaging (MR-US fusion) is already used to guide prostate biopsies and has been proven accurate for diagnosing cervical cancer. In this study, we aimed to evaluate the feasibility and performance of MR-US fusion for characterizing adnexal masses. PATIENTS AND METHODS: A retrospective study was conducted between 2014 and 2018 including women referred to our Gynaecological Oncology Department for characterization of an adnexal mass (n=106). Performance of MR-US fusion was evaluated in a subgroup of patients who underwent surgery (n=26). Two readers, blinded to final histology, performed and rated US findings according to the International Ovarian Tumor Analysis simple rules score, MR according to Ovarian-Adnexal Reporting Data System Magnetic score, and MR-US fusion through a tailored score. The reference outcome was the final pathology. RESULTS: MR-US fusion had a sensitivity of 100% (95%CI=80-100), specificity of 89% (95%CI=52-99), positive likelihood ratio of 9 (95%CI=1.4-57), and accuracy of 96% (95%CI=80-99). CONCLUSION: MR-US fusion is feasible for characterizing adnexal masses to predict ovarian cancer. Copyright
Authors: Wen Ting Xie; Yao Qin Wang; Zhi Sheng Xiang; Zhong Shi Du; Shi Xin Huang; Yi Jie Chen; Li Na Tang Journal: J Ovarian Res Date: 2022-01-23 Impact factor: 4.234