Ayman Elbadawi1, Islam Y Elgendy2, Ahmed H Mohamed3, Mohamed F Almahmoud4, Mohmed Omer5, A Abuzaid6, Karim Mahmoud7, Gbolahan O Ogunbayo8, Ali Denktas9, David Paniagua9, Subhash Banerjee10, Hani Jneid11. 1. Department of Cardiovascular Medicine, University of Texas Medical Branch, Galveston, TX, United States of America. 2. Division of Cardiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States of America. 3. Department of Internal Medicine, Rochester General Hospital, Rochester, NY, United States of America. 4. Division of Cardiovascular Medicine, University of South Carolina, Charleston, SC, United States of America. 5. Minneapolis Heart Institute at Abbott Northwestern Hospital, Minneapolis, MN, United States of America. 6. Division of Cardiovascular Medicine, University of California San Francisco, San Francisco, CA, United States of America. 7. Department of Internal Medicine, Houston Medical Center, Warner Robins, GA, United States of America. 8. Department of Cardiovascular Medicine, University of Kentucky, Lexington, KY, United States of America. 9. Division of Cardiovascular Medicine, Baylor School of Medicine, Houston, TX, United States of America. 10. Division of Cardiovascular Medicine, University of Texas South Western, Dallas, TX, United States of America. 11. Division of Cardiovascular Medicine, Baylor School of Medicine, Houston, TX, United States of America. Electronic address: Jneid@bcm.edu.
Abstract
BACKGROUND: There is a paucity of data regarding the contemporary changes in the uptake and outcomes of transcatheter mitral valve repair (TMVR) and surgical mitral valve repair/replacement (SMVR). METHODS: We queried the NIS database (2012-2016) to identify hospitalizations for TMVR and SMVR. We reported the temporal trends for uptake of TMVR and SMVR and their in-hospital outcomes. RESULTS: The analysis included 77,645 hospitalizations: 8760 (11.3%) for TMVR and 68,885 (88.7%) for SMVR. Those undergoing TMVR were older and had a higher prevalence of comorbidities, but shorter length of stay (5.5 ± 8.8 vs. 14.3 ± 13.8, p < 0.001) compared with SMVR. There was a marked increase in the number of TMVRs over time (from 420 in 2012 to 3850 in 2016; +917%; Ptrend = 0.008) but a modest increase in the number of SMVRs (+117%; Ptrend = 0.02). Overall, TMVR was associated with low in-hospital mortality (2%) and favorable safety profile. After adjusting for clinical and hospital variables, there were non-significant trends towards lower adjusted mortality among TMVR and SMVR (Ptrend = 0.16 and Ptrend = 0.13, respectively). Notably, among TMVR patients, female sex was associated with lower in-hospital mortality while CKD was associated with increased in-hospital mortality. There was a significant downtrend in the incidences of cardiac arrest, hemodialysis and length of stay in TMVR patients. CONCLUSION: Real world data showed a steady increase in the number of TMVR and SMVR procedures. Overall, TMVR was associated with low in-hospital mortality and complications rates. Despite older age and increased comorbidities, TMVR patients had lower in-hospital mortality and shorter length than their SMVR counterparts. Published by Elsevier Inc.
BACKGROUND: There is a paucity of data regarding the contemporary changes in the uptake and outcomes of transcatheter mitral valve repair (TMVR) and surgical mitral valve repair/replacement (SMVR). METHODS: We queried the NIS database (2012-2016) to identify hospitalizations for TMVR and SMVR. We reported the temporal trends for uptake of TMVR and SMVR and their in-hospital outcomes. RESULTS: The analysis included 77,645 hospitalizations: 8760 (11.3%) for TMVR and 68,885 (88.7%) for SMVR. Those undergoing TMVR were older and had a higher prevalence of comorbidities, but shorter length of stay (5.5 ± 8.8 vs. 14.3 ± 13.8, p < 0.001) compared with SMVR. There was a marked increase in the number of TMVRs over time (from 420 in 2012 to 3850 in 2016; +917%; Ptrend = 0.008) but a modest increase in the number of SMVRs (+117%; Ptrend = 0.02). Overall, TMVR was associated with low in-hospital mortality (2%) and favorable safety profile. After adjusting for clinical and hospital variables, there were non-significant trends towards lower adjusted mortality among TMVR and SMVR (Ptrend = 0.16 and Ptrend = 0.13, respectively). Notably, among TMVR patients, female sex was associated with lower in-hospital mortality while CKD was associated with increased in-hospital mortality. There was a significant downtrend in the incidences of cardiac arrest, hemodialysis and length of stay in TMVR patients. CONCLUSION: Real world data showed a steady increase in the number of TMVR and SMVR procedures. Overall, TMVR was associated with low in-hospital mortality and complications rates. Despite older age and increased comorbidities, TMVR patients had lower in-hospital mortality and shorter length than their SMVR counterparts. Published by Elsevier Inc.
Authors: Guisela Flores; Dolores Mesa; Soledad Ojeda; Javier Suárez de Lezo; Rafael Gonzalez-Manzanares; Guillermo Dueñas; Manuel Pan Journal: J Clin Med Date: 2022-08-14 Impact factor: 4.964
Authors: Katharina Schnitzler; Michaela Hell; Martin Geyer; Felix Kreidel; Thomas Münzel; Ralph Stephan von Bardeleben Journal: Curr Cardiol Rep Date: 2021-08-13 Impact factor: 2.931