Literature DB >> 32619511

Is Obesity a Disease of Stem Cells?

Arin K Oestreich1, Kelsey H Collins1, Natalia S Harasymowicz1, Chia-Lung Wu1, Farshid Guilak2.   

Abstract

Obesity disrupts physiological homeostasis and alters both systemic and local microenvironments that impact stem cell plasticity and impair regenerative capacity. We present growing evidence that reveals the bidirectionality of obesity-induced stem cell dysfunction and how the molecular changes in stem cells residing in obese environments may accelerate disease severity.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Year:  2020        PMID： 32619511      PMCID： PMC8715393          DOI： 10.1016/j.stem.2020.04.019

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


  10 in total

Review 1.  Mitochondria in early development: linking the microenvironment, metabolism and the epigenome.

Authors:  Alexandra J Harvey
Journal:  Reproduction       Date:  2019-05-01       Impact factor: 3.906

2.  Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice.

Authors:  Chelsea Hepler; Bo Shan; Qianbin Zhang; Gervaise H Henry; Mengle Shao; Lavanya Vishvanath; Alexandra L Ghaben; Angela B Mobley; Douglas Strand; Gary C Hon; Rana K Gupta
Journal:  Elife       Date:  2018-09-28       Impact factor: 8.140

3.  Maternal Metabolic Syndrome Programs Mitochondrial Dysfunction via Germline Changes across Three Generations.

Authors:  Jessica L Saben; Anna L Boudoures; Zeenat Asghar; Alysha Thompson; Andrea Drury; Wendy Zhang; Maggie Chi; Andrew Cusumano; Suzanne Scheaffer; Kelle H Moley
Journal:  Cell Rep       Date:  2016-06-16       Impact factor: 9.423

4.  Identification of a mesenchymal progenitor cell hierarchy in adipose tissue.

Authors:  David Merrick; Alexander Sakers; Zhazira Irgebay; Chihiro Okada; Catherine Calvert; Michael P Morley; Ivona Percec; Patrick Seale
Journal:  Science       Date:  2019-04-26       Impact factor: 47.728

Review 5.  Insight into the development of obesity: functional alterations of adipose-derived mesenchymal stem cells.

Authors:  F Louwen; A Ritter; N N Kreis; J Yuan
Journal:  Obes Rev       Date:  2018-03-08       Impact factor: 9.213

6.  Thy-1 (CD90) promotes bone formation and protects against obesity.

Authors:  Ann-Kristin Picke; Graeme M Campbell; Matthias Blüher; Ute Krügel; Felix N Schmidt; Elena Tsourdi; Maria Winzer; Martina Rauner; Vladimir Vukicevic; Björn Busse; Juliane Salbach-Hirsch; Jan P Tuckermann; Jan C Simon; Ulf Anderegg; Lorenz C Hofbauer; Anja Saalbach
Journal:  Sci Transl Med       Date:  2018-08-08       Impact factor: 17.956

7.  Diet-induced obesity alters the differentiation potential of stem cells isolated from bone marrow, adipose tissue and infrapatellar fat pad: the effects of free fatty acids.

Authors:  C-L Wu; B O Diekman; D Jain; F Guilak
Journal:  Int J Obes (Lond)       Date:  2012-11-20       Impact factor: 5.095

8.  Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis.

Authors:  Mikolaj Ogrodnik; Yi Zhu; Larissa G P Langhi; Tamar Tchkonia; Patrick Krüger; Edward Fielder; Stella Victorelli; Rifqha A Ruswhandi; Nino Giorgadze; Tamar Pirtskhalava; Oleg Podgorni; Grigori Enikolopov; Kurt O Johnson; Ming Xu; Christine Inman; Allyson K Palmer; Marissa Schafer; Moritz Weigl; Yuji Ikeno; Terry C Burns; João F Passos; Thomas von Zglinicki; James L Kirkland; Diana Jurk
Journal:  Cell Metab       Date:  2019-05-07       Impact factor: 27.287

9.  IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes.

Authors:  Juxue Li; Yizhe Tang; Dongsheng Cai
Journal:  Nat Cell Biol       Date:  2012-09-02       Impact factor: 28.824

10.  Diet-induced obesity promotes myelopoiesis in hematopoietic stem cells.

Authors:  Kanakadurga Singer; Jennifer DelProposto; David Lee Morris; Brian Zamarron; Taleen Mergian; Nidhi Maley; Kae Won Cho; Lynn Geletka; Perla Subbaiah; Lindsey Muir; Gabriel Martinez-Santibanez; Carey Nien-Kai Lumeng
Journal:  Mol Metab       Date:  2014-07-10       Impact factor: 7.422
  10 in total
  1 in total

1.  Trappc9 Deficiency Impairs the Plasticity of Stem Cells.

Authors:  Muhammad Usman; Yan Li; Yuting Ke; Gaurav Chhetri; Md Ariful Islam; Zejian Wang; Xueyi Li
Journal:  Int J Mol Sci       Date:  2022-04-28       Impact factor: 6.208
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.