Literature DB >> 32618456

Impact of Oral Care and Antisepsis on the Prevalence of Ventilator-Associated Pneumonia.

Luciana F Galhardo, Gilson F Ruivo, Fernanda O Santos, Tamires T Ferreira, Juliana Santos, Mariella Vp L Eão, Debora Pallos.   

Abstract

PURPOSE: This study aimed to evaluate the impact of oral care and use of chlorhexidine gluconate on the prevention of ventilator-associated pneumonia (VAP) in patients admitted to an intensive care unit (ICU).
MATERIALS AND METHODS: An evaluation was performed on 229 patients admitted to ICU in 2012 (before implementation of oral care protocol) and 329 in 2013 (after the protocol). Oral care was based on the removal of secretions from the oral cavity with 0.12% chlorhexidine solution for brushing and sterile gauze for cleaning before a new aspiration. The cases of VAP were evaluated by observing respiratory signs, radiological changes, and culture and laboratory results. The following data were also analysed: gender, length hospital of stay, mechanical ventilation, use of antibiotics and aetiological agent of infection.
RESULTS: There was a tendency towards lower risk of development of VAP after application of oral care protocol (odds ratio = 0.64-95% CI: 0.39-1.04). There was also a reduction in the incidence of early pneumonia (up to 72 h of hospitalisation). With regard to the aetiological agent of infections, although Gram-negative bacteria predominated in the two periods studied, there was a decrease in the cases of Staphylococcus aureus infection.
CONCLUSION: Oral care protocol has statistically significantly reduced the risk of developing early VAP in ICU patients, thus demonstrating the importance of multidisciplinary teamwork for hospitalised patients.

Entities:  

Keywords:  chlorhexidine; mechanical ventilation; oral care; pneumonia

Mesh:

Year:  2020        PMID: 32618456     DOI: 10.3290/j.ohpd.a44443

Source DB:  PubMed          Journal:  Oral Health Prev Dent        ISSN: 1602-1622            Impact factor:   1.256


  4 in total

1.  [A review on the characteristics of microbiome and their association with diseases in preterm infants].

Authors:  Qiong Jia; Xiao-Mei Tong
Journal:  Zhongguo Dang Dai Er Ke Za Zhi       Date:  2020-11

2.  Using Restricted Cubic Splines to Study the Duration of Antibiotic Use in the Prognosis of Ventilator-Associated Pneumonia.

Authors:  Yixian Xu; Didi Han; Fengshuo Xu; Si Shen; Xinkai Zheng; Hao Wang; Jun Lyu
Journal:  Front Pharmacol       Date:  2022-04-29       Impact factor: 5.988

Review 3.  Relationships Between Oral Microecosystem and Respiratory Diseases.

Authors:  Jiajia Dong; Wei Li; Qi Wang; Jiahao Chen; Yue Zu; Xuedong Zhou; Qiang Guo
Journal:  Front Mol Biosci       Date:  2022-01-04

4.  Meta-Analysis of the Efficacy and Safety of Chlorhexidine for Ventilator-Associated Pneumonia Prevention in Mechanically Ventilated Patients.

Authors:  Weiying Dai; Yao Lin; Xiangying Yang; Pei Huang; Liuqin Xia; Jianping Ma
Journal:  Evid Based Complement Alternat Med       Date:  2022-07-30       Impact factor: 2.650

  4 in total

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