Literature DB >> 32617227

Metastatic Malignant Melanoma Mimicking Mammary Mass: A Rare Presentation.

Ankit Jain1, Chellappa Vijayakumar1, Uday Kumbhar1, Sudharsanan Sundaramurthi1, Gopal Balasubramanian1.   

Abstract

Breast lump in perimenopausal women is considered a primary malignancy unless proved otherwise. Metastasis to the breast from extramammary sites is rare. Malignant melanoma (MM) is known for its ability to spread to distant sites, which can be both hematogenous and lymphatic. The common sites are skin, lung, liver, brain, etc. However, reports of melanoma metastasizing to the breast are rare. We present a case of 50-year-old female patient, who underwent wide local excision and split skin grafting for MM right leg. She did not undergo any adjuvant therapy and one year later presented to us with a solitary lump occupying the upper inner quadrant of the right breast. The breast lump turned out to be metastatic deposit from MM based on the presence of melanin in cells on fine needle aspiration cytology (FNAC). Therefore, breast lump in perimenopausal is not always a primary malignancy, and differential diagnosis should also include metastatic tumors.
Copyright © 2020, Jain et al.

Entities:  

Keywords:  carcinoma breast; melanoma; metastsis

Year:  2020        PMID: 32617227      PMCID: PMC7325399          DOI: 10.7759/cureus.8354

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  7 in total

1.  Breast metastasis from a melanoma.

Authors:  Ahmad Al Samaraee; Hazem Khout; Tarig Barakat; Tarannum Fasih
Journal:  Ochsner J       Date:  2012

2.  Metastatic disease to the breast: clinical, pathologic, and radiographic features.

Authors:  B D Toombs; L Kalisher
Journal:  AJR Am J Roentgenol       Date:  1977-10       Impact factor: 3.959

Review 3.  Treatment of metastatic malignant melanoma.

Authors:  Ehab Atallah; Lawrence Flaherty
Journal:  Curr Treat Options Oncol       Date:  2005-05

4.  Metastatic disease in the breast.

Authors:  M N Akçay
Journal:  Breast       Date:  2002-12       Impact factor: 4.380

5.  Amelanotic Signet Ring Cell Melanoma Presenting as Breast Lump- A Diagnostic Conundrum.

Authors:  Prasath Sathiah; Debasis Gochhait; Subathra Adithan; Sandhya Umamahesweran; Priyadarshini Dehuri
Journal:  J Clin Diagn Res       Date:  2017-08-01

6.  Metastatic breast disease from cutaneous malignant melanoma.

Authors:  Marco Moschetta; Michele Telegrafo; Nicola Maria Lucarelli; Gianluigi Martino; Leonarda Rella; Amato Antonio Stabile Ianora; Giuseppe Angelelli
Journal:  Int J Surg Case Rep       Date:  2013-11-28

7.  Primary malignant melanoma of the breast: A case report and review of the literature.

Authors:  Yujun He; Jianghong Mou; Donglin Luo; Bo Gao; Yayuan Wen
Journal:  Oncol Lett       Date:  2014-05-07       Impact factor: 2.967

  7 in total
  1 in total

1.  Metastatic Malignant Melanoma With Occult Primary Presenting as Breast Mass: A Case Report and Literature Review.

Authors:  Rebecca M Harsten; Rebecca Fisher; Nazar Al-Sanjari; Philip Idaewor; Abdalla Saad Abdalla Al-Zawi
Journal:  Cureus       Date:  2021-06-24
  1 in total

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