OBJECTIVE: Osteochondral lesions of the knee affect patients from all age groups with arthroscopic microfracture being the current gold standard of treatment of such lesions. Autologous collagen-induced chondrogenesis (ACIC) is a novel procedure that has recently been gaining popularity. This study aims to compare the 6 and 24 month post-operative outcomes between patients undergoing microfracture only and microfracture with ACIC. METHODS: Patients from both groups were assessed pre-operatively, at 6 and 24 months post-operatively for functional outcomes using SF-36 and IKDC scoring (International Knee Documentation Committee Subjective Knee Form). RESULTS: Both groups showed improved SF-36 and IKDC scores at 6 and 24 months, however patients who underwent ACIC showed better SF-36 mental component and IKDC scores 24 months after surgery. CONCLUSION: This demonstrates that ACIC is an effective, single-stage, joint-preserving procedure which is comparable, if not better, in treating chondral defects.
OBJECTIVE: Osteochondral lesions of the knee affect patients from all age groups with arthroscopic microfracture being the current gold standard of treatment of such lesions. Autologous collagen-induced chondrogenesis (ACIC) is a novel procedure that has recently been gaining popularity. This study aims to compare the 6 and 24 month post-operative outcomes between patients undergoing microfracture only and microfracture with ACIC. METHODS: Patients from both groups were assessed pre-operatively, at 6 and 24 months post-operatively for functional outcomes using SF-36 and IKDC scoring (International Knee Documentation Committee Subjective Knee Form). RESULTS: Both groups showed improved SF-36 and IKDC scores at 6 and 24 months, however patients who underwent ACIC showed better SF-36 mental component and IKDC scores 24 months after surgery. CONCLUSION: This demonstrates that ACIC is an effective, single-stage, joint-preserving procedure which is comparable, if not better, in treating chondral defects.
Authors: Philipp Niemeyer; Stella Porichis; Matthias Steinwachs; Christoph Erggelet; Peter C Kreuz; Hagen Schmal; Markus Uhl; Nadir Ghanem; Norbert P Südkamp; Gian Salzmann Journal: Am J Sports Med Date: 2013-10-21 Impact factor: 6.202
Authors: Filippo Migliorini; Hanno Schenker; Nicola Maffulli; Jörg Eschweiler; Philipp Lichte; Frank Hildebrand; Christian David Weber Journal: Sci Rep Date: 2022-09-28 Impact factor: 4.996