Literature DB >> 32616534

Ciprofloxacin/dexamethasone precipitate formation in the ear canal of a paediatric patient.

Stacey D Curtis1, Eric F Egelund2, Alex M Ebied3.   

Abstract

This case report describes a paediatric patient diagnosed with otitis externa and treated with topical ciprofloxacin/dexamethasone. The patient completed the course of therapy and then developed precipitate formation from the pharmacological treatment. Laboratory testing of the precipitate confirmed the presence of a large quantity of ciprofloxacin. Removal of the precipitate required the use of an elephant ear washer system and removal with surgical tweezers. This case report investigated a probable topical ciprofloxacin/dexamethasone-induced ear precipitate formation in the ear canal, which, subsequently, was successfully removed from the patient's ear canal. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  ear, nose and throat; paediatrics; unwanted effects / adverse reactions

Mesh:

Substances:

Year:  2020        PMID: 32616534      PMCID: PMC7333803          DOI: 10.1136/bcr-2020-234290

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  4 in total

Review 1.  Otitis externa.

Authors:  Daniel Hajioff; Samuel MacKeith
Journal:  BMJ Clin Evid       Date:  2015-06-15

2.  A method for estimating the probability of adverse drug reactions.

Authors:  C A Naranjo; U Busto; E M Sellers; P Sandor; I Ruiz; E A Roberts; E Janecek; C Domecq; D J Greenblatt
Journal:  Clin Pharmacol Ther       Date:  1981-08       Impact factor: 6.875

3.  Topical ciprofloxacin/dexamethasone is superior to ciprofloxacin alone in pediatric patients with acute otitis media and otorrhea through tympanostomy tubes.

Authors:  Peter S Roland; Jack B Anon; Richard D Moe; Peter J Conroy; G Michael Wall; Sheryl J Dupre; Kimberly A Krueger; Susan Potts; Gail Hogg; David W Stroman
Journal:  Laryngoscope       Date:  2003-12       Impact factor: 3.325

4.  Topical ciprofloxacin/dexamethasone otic suspension is superior to ofloxacin otic solution in the treatment of children with acute otitis media with otorrhea through tympanostomy tubes.

Authors:  Peter S Roland; Leslie S Kreisler; Bradley Reese; Jack B Anon; Brent Lanier; Peter J Conroy; G Michael Wall; Sheryl J Dupre; Susan Potts; Gail Hogg; David W Stroman; Celeste McLean
Journal:  Pediatrics       Date:  2004-01       Impact factor: 7.124

  4 in total

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