Vedangi Arvind Mohite1, Sudhindra Baliga1, Nilima Thosar1, Nilesh Rathi1, Pramod Khobragade2, Rashi Srivastava1. 1. Department of Pediatric and Preventive Dentistry, Sharad Pawar Dental College and Hospital, Datta Meghe Institute of Medical Sciences (Deemed to be University), Wardha, Maharashtra, India. 2. Department of Pharmacology and Materia Medica, Datta Meghe Institute of Ayurvedic Medical College, Hospital and Research Centre, Nagpur, Maharashtra, India.
Abstract
BACKGROUND: Topical anesthetics have an intrinsic part to reduce pricking pain sensation due to needle stick before injection in children. AIM: The present study aimed to determine the effectiveness of a novel herbal anesthetic gel used as a topical anesthetic before an inferior alveolar nerve block. SETTINGSAND DESIGN: This was a bilateral split-mouth, single blind, crossoverin vivo study. METHODS: Atotal number of 30 children were selected for this study design. After the application of the topical anesthesia, a 26-gauge needle was inserted in the mucobuccal fold and local anesthetic solution was deposited. Assessment of pain perception was done before the procedure and at the time of needle penetration using hemodynamic parameters such as blood pressure and heart rate. The objective and subjective pain assessment was recoded through sound eye motor scale and Faces Pain Scale-Revised (FPS-R). STATISTICALANALYSIS: As the data followed a normal distribution, parametric tests were used to analyze these data. The independent sample t-test and paired sample t-test were used to check the mean differences. RESULTS: The data showed no statistically significant differences in the objective and subjective pain assessment values of the novel herbal anesthetic gel compared to the 2% lignocaine gel. However, the intragroup comparisons of the before and during treatment results showed statistically significant results (P < 0.05). CONCLUSION: The novel herbal anesthetic gel was effective and safe in reducing the pain from needle insertion. Thus, setting up scientific evidence for the therapeutic usage of herbal products can, therefore, assist to develop a more efficient and alternative topical anesthetic.
BACKGROUND: Topical anesthetics have an intrinsic part to reduce pricking pain sensation due to needle stick before injection in children. AIM: The present study aimed to determine the effectiveness of a novel herbal anesthetic gel used as a topical anesthetic before an inferior alveolar nerve block. SETTINGSAND DESIGN: This was a bilateral split-mouth, single blind, crossoverin vivo study. METHODS: Atotal number of 30 children were selected for this study design. After the application of the topical anesthesia, a 26-gauge needle was inserted in the mucobuccal fold and local anesthetic solution was deposited. Assessment of pain perception was done before the procedure and at the time of needle penetration using hemodynamic parameters such as blood pressure and heart rate. The objective and subjective pain assessment was recoded through sound eye motor scale and Faces Pain Scale-Revised (FPS-R). STATISTICALANALYSIS: As the data followed a normal distribution, parametric tests were used to analyze these data. The independent sample t-test and paired sample t-test were used to check the mean differences. RESULTS: The data showed no statistically significant differences in the objective and subjective pain assessment values of the novel herbal anesthetic gel compared to the 2% lignocaine gel. However, the intragroup comparisons of the before and during treatment results showed statistically significant results (P < 0.05). CONCLUSION: The novel herbal anesthetic gel was effective and safe in reducing the pain from needle insertion. Thus, setting up scientific evidence for the therapeutic usage of herbal products can, therefore, assist to develop a more efficient and alternative topical anesthetic.
Entities:
Keywords:
2% lignocaine gel; faces pain scale-revised scale; sound eye motor scale; topical anesthetic gel
Authors: Raghavendra Havale; Dhanu G Rao; Shrutha S P; Kanchan M Tuppadmath; Namratha Tharay; Irin Mathew; Kausar E Taj Journal: J Dent Anesth Pain Med Date: 2021-07-30