Literature DB >> 3260848

Bilateral upper lobe Pneumocystis carinii pneumonia in a patient receiving inhaled pentamidine prophylaxis.

A G Abd1, D M Nierman, J S Ilowite, R N Pierson, A L Bell.   

Abstract

A 46-year-old man with AIDS, receiving inhaled pentamidine for Pneumocystis carinii pneumonia (PCP) prophylaxis, developed bilateral upper lobe infiltrates. Bronchoalveolar lavage confirmed the diagnosis of PCP. Therapy with intravenous trimethoprim-sulfamethoxazole (TMP-SMX) was begun, with gradual resolution of these infiltrates noted. An explanation for the development of upper lobe PCP, despite aerosol chemoprophylaxis, is presented and emphasizes the importance of aerosol particle size (and therefore of nebulizer type) on the distribution of inhaled pentamidine.

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Year:  1988        PMID： 3260848     DOI： 10.1378/chest.94.2.329

Source DB:  PubMed          Journal:  Chest        ISSN： 0012-3692            Impact factor:   9.410


  10 in total

Review 1.  Pneumocystis carinii pneumonia.

Authors:  S Thomas; M O'Doherty; N Bateman
Journal:  BMJ       Date:  1990-01-27

Review 2.  Pneumocystis carinii, an opportunist in immunocompromised patients.

Authors:  M S Bartlett; J W Smith
Journal:  Clin Microbiol Rev       Date:  1991-04       Impact factor: 26.132

3.  Compliance and laboratory data predict relapse rate of Pneumocystis carinii pneumonia during prophylaxis with aerosol pentamidine.

Authors:  M Opravil; R Weber; B Ledergerber; R Speich; W Siegenthaler; R Lüthy
Journal:  Klin Wochenschr       Date:  1990-04-17

Review 4.  Inhaled pentamidine. An overview of its pharmacological properties and a review of its therapeutic use in Pneumocystis carinii pneumonia.

Authors:  J P Monk; P Benfield
Journal:  Drugs       Date:  1990-05       Impact factor: 9.546

Review 5.  Pentamidine. A risk-benefit analysis.

Authors:  B Wispelwey; R Pearson
Journal:  Drug Saf       Date:  1990 May-Jun       Impact factor: 5.606

6.  Relapse of Pneumocystis carinii pneumonia in the upper lobes during aerosol pentamidine prophylaxis.

Authors:  R M Bradburne; D B Ettensohn; S M Opal; F D McCool
Journal:  Thorax       Date:  1989-07       Impact factor: 9.139

7.  Apical Pneumocystis jiroveci as an AIDS defining illness: A case report illustrating a change in the paradigm.

Authors:  Kyle Pfeifer; Vivek Kalra; Adeniran Adebowale; Manisha Juthani-Mehta; Myung Soo-Shin
Journal:  J Radiol Case Rep       Date:  2014-11-30

8.  Antibiotic penetration into lung tissues.

Authors:  D Honeybourne
Journal:  Thorax       Date:  1994-02       Impact factor: 9.139

9.  Aerosolized L-693,989 for Pneumocystis carinii prophylaxis in rats.

Authors:  M A Powles; D C McFadden; P A Liberator; J W Anderson; E B Vadas; D Meisner; D M Schmatz
Journal:  Antimicrob Agents Chemother       Date:  1994-06       Impact factor: 5.191

10.  Upper lobe relapse of Pneumocystis carinii pneumonia during aerosolized pentamidine prophylaxis.

Authors:  S Köppen; T Grünewald; G Jautzke; B Ruf
Journal:  Klin Wochenschr       Date:  1991-07-22
  10 in total

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