Eri Oda1, Toru Beppu2, Koichi Kinoshita1, Kensuke Yamamura1, Nobutaka Sato1, Hideaki Yuki3, Suguru Chiyonaga4, Toshihiko Motohara4, Yoshihiko Komohara5, Shinichi Akahoshi1. 1. Department of Surgery, Yamaga City Medical Center, Kumamoto, Japan. 2. Department of Surgery, Yamaga City Medical Center, Kumamoto, Japan tbeppu@yamaga-mc.jp. 3. Department of Radiology, Yamaga City Medical Center, Kumamoto, Japan. 4. Department of Gastroenterology, Yamaga City Medical Center, Kumamoto, Japan. 5. Department of Cell Pathology, Graduate School of Medicine, Kumamoto University, Kumamoto, Japan.
Abstract
BACKGROUND/AIM: Hepatic xanthogranuloma is a very rale disease and formation process is unknown. CASE REPORT: A 69-year-old woman previously diagnosed as simple liver cyst. Two years before, a 36-mm liver cyst was found in segment 5, while one year later, the hemorrhagic cyst was 40 mm in diameter and a thin septum had formed. The most recent T1-weighted magnetic resonance imaging (MRI) showed a regular 21-mm hepatic mass with a hyperintense 11-mm center and a hypointense periphery. Peripheral enhancement was seen on gadolinium enhanced MRI. Hepatobiliary cystadenoma or cystadenocarcinoma was suspected because of wall thickness and slight enhancement. Microscopic examination following laparoscopic partial liver resection revealed fibroblasts, dense collagen fibers, and a double layer of hemosiderin-laden as well as foamy macrophages attached to the fibrous capsule. CONCLUSION: The patient was diagnosed with a hepatic xanthogranuloma that originated from a hemorrhagic liver cyst. Intracystic hemorrhage may be one of the reasons for hepatic xanthogranuloma formation. Copyright
BACKGROUND/AIM: Hepatic xanthogranuloma is a very rale disease and formation process is unknown. CASE REPORT: A 69-year-old woman previously diagnosed as simple liver cyst. Two years before, a 36-mm liver cyst was found in segment 5, while one year later, the hemorrhagic cyst was 40 mm in diameter and a thin septum had formed. The most recent T1-weighted magnetic resonance imaging (MRI) showed a regular 21-mm hepatic mass with a hyperintense 11-mm center and a hypointense periphery. Peripheral enhancement was seen on gadolinium enhanced MRI. Hepatobiliary cystadenoma or cystadenocarcinoma was suspected because of wall thickness and slight enhancement. Microscopic examination following laparoscopic partial liver resection revealed fibroblasts, dense collagen fibers, and a double layer of hemosiderin-laden as well as foamy macrophages attached to the fibrous capsule. CONCLUSION: The patient was diagnosed with a hepatic xanthogranuloma that originated from a hemorrhagic liver cyst. Intracystic hemorrhage may be one of the reasons for hepatic xanthogranuloma formation. Copyright
Authors: K Tyson Thomas; Derek Welch; Andrew Trueblood; Paulgun Sulur; Paul Wise; D Lee Gorden; Ravi S Chari; J Kelly Wright; Kay Washington; C Wright Pinson Journal: Ann Surg Date: 2005-05 Impact factor: 12.969
Authors: T Nakajima; I Sugano; O Matsuzaki; K Nagao; Y Kondo; M Miyazaki; A Konno; T Shimura Journal: Arch Pathol Lab Med Date: 1993-02 Impact factor: 5.534