BACKGROUND/AIM: Although ABO blood group has been reported to be associated with the outcome of patients with pancreatic cancer, little is known about its impact on patients with biliary tract cancer (BTC). We evaluated the prognostic relevance of ABO blood group in patients who had undergone resection of BTC. PATIENTS AND METHODS: A total of 154 patients with BTC undergoing pancreatoduodenectomy were retrospectively reviewed. Associations between ABO blood group and patient survival were evaluated by univariate and multivariate analysis. RESULTS: The 5-year overall survival rate was higher in group O patients (n=46) than in other blood group patients (n=108) (65.8% vs. 47%, p=0.005). Multivariate analysis revealed that a non-O blood group was an independent risk factor for poor survival (p=0.021). CONCLUSION: ABO blood group is associated with the prognosis of patients with resected BTC; group O patients have a better outcome. Copyright
BACKGROUND/AIM: Although ABO blood group has been reported to be associated with the outcome of patients with pancreatic cancer, little is known about its impact on patients with biliary tract cancer (BTC). We evaluated the prognostic relevance of ABO blood group in patients who had undergone resection of BTC. PATIENTS AND METHODS: A total of 154 patients with BTC undergoing pancreatoduodenectomy were retrospectively reviewed. Associations between ABO blood group and patient survival were evaluated by univariate and multivariate analysis. RESULTS: The 5-year overall survival rate was higher in group O patients (n=46) than in other blood group patients (n=108) (65.8% vs. 47%, p=0.005). Multivariate analysis revealed that a non-O blood group was an independent risk factor for poor survival (p=0.021). CONCLUSION:ABO blood group is associated with the prognosis of patients with resected BTC; group O patients have a better outcome. Copyright
Authors: Maja Barbalic; Josée Dupuis; Abbas Dehghan; Joshua C Bis; Ron C Hoogeveen; Renate B Schnabel; Vijay Nambi; Monique Bretler; Nicholas L Smith; Annette Peters; Chen Lu; Russell P Tracy; Nena Aleksic; Jan Heeriga; John F Keaney; Kenneth Rice; Gregory Y H Lip; Ramachandran S Vasan; Nicole L Glazer; Martin G Larson; Andre G Uitterlinden; Jennifer Yamamoto; Peter Durda; Talin Haritunians; Bruce M Psaty; Eric Boerwinkle; Albert Hofman; Wolfgang Koenig; Nancy S Jenny; Jacqueline C Witteman; Christie Ballantyne; Emelia J Benjamin Journal: Hum Mol Genet Date: 2010-02-18 Impact factor: 6.150
Authors: Giovanni Marfia; Stefania Elena Navone; Claudia Fanizzi; Silvia Tabano; Chiara Pesenti; Loubna Abdel Hadi; Andrea Franzini; Manuela Caroli; Monica Miozzo; Laura Riboni; Paolo Rampini; Rolando Campanella Journal: Cancer Med Date: 2016-05-28 Impact factor: 4.452