Literature DB >> 32605374

Cytokine Storm in COVID19: A Neural Hypothesis.

Anoop Ur1, Kavita Verma1.   

Abstract

Cytokine storm in COVID-19 is characterized by an excessive inflammatory response to SARS-CoV-2 that is caused by a dysregulated immune system of the host. We are proposing a new hypothesis that SARS-CoV-2 mediated inflammation of nucleus tractus solitarius (NTS) may be responsible for the cytokine storm in COVID 19. The inflamed NTS may result in a dysregulated cholinergic anti-inflammatory pathway and hypothalamic-pituitary-adrenal axis.

Entities:  

Keywords:  COVID-19; cholinergic anti-inflammatory pathway; cytokine storm; cytokines; hypothalamic−pituitary−adrenal axis; nucleus tractus solitarius

Mesh：

Substances：

Year:  2020        PMID： 32605374     DOI： 10.1021/acschemneuro.0c00346

Source DB:  PubMed          Journal:  ACS Chem Neurosci        ISSN： 1948-7193            Impact factor:   4.418


  10 in total

1.  Adrenal crisis in a patient with APS2 due to COVID-19: A case report.

Authors:  Varun Suryadevara; Chandhana Merugu; Nandhini L Perumal; Jayaprakash Sahoo; Sadishkumar Kamalanathan; Dukhabandhu Naik
Journal:  J Family Med Prim Care       Date:  2022-05-14

Review 2.  Targeting Specific Checkpoints in the Management of SARS-CoV-2 Induced Cytokine Storm.

Authors:  Abdullahi Rabiu Abubakar; Rahnuma Ahmad; Adekunle Babajide Rowaiye; Sayeeda Rahman; Katia Iskandar; Siddhartha Dutta; Angus Nnamdi Oli; Sameer Dhingra; Maryam Abba Tor; Ayukafangha Etando; Santosh Kumar; Mohammed Irfan; Marshall Gowere; Kona Chowdhury; Farhana Akter; Dilshad Jahan; Natalie Schellack; Mainul Haque
Journal:  Life (Basel)       Date:  2022-03-25

3.  A Translational Perspective of Maternal Immune Activation by SARS-CoV-2 on the Potential Prenatal Origin of Neurodevelopmental Disorders: The Role of the Cholinergic Anti-inflammatory Pathway.

Authors:  José Javier Reyes-Lagos; Eric Alonso Abarca-Castro; Juan Carlos Echeverría; Hugo Mendieta-Zerón; Alejandra Vargas-Caraveo; Gustavo Pacheco-López
Journal:  Front Psychol       Date:  2021-03-31

Review 4.  The Unfolding Palette of COVID-19Multisystemic Syndrome and its Neurological Manifestations.

Authors:  Francisco J Barrantes
Journal:  Brain Behav Immun Health       Date:  2021-04-03

Review 5.  Elucidating the Neuropathologic Mechanisms of SARS-CoV-2 Infection.

Authors:  Mar Pacheco-Herrero; Luis O Soto-Rojas; Charles R Harrington; Yazmin M Flores-Martinez; Marcos M Villegas-Rojas; Alfredo M León-Aguilar; Paola A Martínez-Gómez; B Berenice Campa-Córdoba; Ricardo Apátiga-Pérez; Carolin N Corniel-Taveras; Jesabelle de J Dominguez-García; Víctor Manuel Blanco-Alvarez; José Luna-Muñoz
Journal:  Front Neurol       Date:  2021-04-12       Impact factor: 4.003

6.  Mesenchymal stem cell immunomodulation: In pursuit of controlling COVID-19 related cytokine storm.

Authors:  Na Song; Hiroaki Wakimoto; Filippo Rossignoli; Deepak Bhere; Rachele Ciccocioppo; Kok-Siong Chen; Jasneet Kaur Khalsa; Ilenia Mastrolia; Anna Valeria Samarelli; Massimo Dominici; Khalid Shah
Journal:  Stem Cells       Date:  2021-03-07       Impact factor: 5.845

Review 7.  Severe Acute Respiratory Syndrome Coronavirus 2-Induced Neurological Complications.

Authors:  Shijia Yu; Mingjun Yu
Journal:  Front Cell Dev Biol       Date:  2020-12-10

Review 8.  How COVID-19 can cause autonomic dysfunctions and postural orthostatic syndrome? A Review of mechanisms and evidence.

Authors:  Mehran Hassani; Ali Fathi Jouzdani; Sara Motarjem; Akram Ranjbar; Nakisa Khansari
Journal:  Neurol Clin Neurosci       Date:  2021-10-26

Review 9.  Potential relationships between COVID-19 and the thyroid gland: an update.

Authors:  Rania Naguib
Journal:  J Int Med Res       Date:  2022-02       Impact factor: 1.671

10.  DNA aptamers inhibit SARS-CoV-2 spike-protein binding to hACE2 by an RBD- independent or dependent approach.

Authors:  Achut Prasad Silwal; Siddhartha Kalpa Samadhi Thennakoon; Satya Prakash Arya; Rick Mason Postema; Raunak Jahan; Chien Minh Tran Phuoc; Xiaohong Tan
Journal:  Theranostics       Date:  2022-07-18       Impact factor: 11.600
  10 in total

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