| Literature DB >> 32603470 |
Samuel S Gordon1, John Hollowed2, Justin Hayase2, Carlos Macias2, Jessica Wang2, Holly R Middlekauff2.
Abstract
Acquired long QT syndrome is typically caused by medications, electrolyte disturbances, bradycardia, or catastrophic central nervous system events. We report a case of myocardial infarction-related acquired long QT syndrome in a 58-year-old woman that had no clear cause and progressed to torsades de pointes requiring treatment with isoproterenol and magnesium. Despite negative results of DNA testing against a known panel of genetic mutations and polymorphisms associated with long QT syndrome, the patient's family history of fatal cardiac disease suggests a predisposing genetic component. This report serves to remind clinicians of this potentially fatal ventricular arrhythmia after myocardial infarction.Entities:
Keywords: Long QT syndrome/etiology/genetics; myocardial infarction; torsades de pointes
Year: 2020 PMID: 32603470 PMCID: PMC7328093 DOI: 10.14503/THIJ-18-6872
Source DB: PubMed Journal: Tex Heart Inst J ISSN: 0730-2347