Prediction of quality of life in a cohort of end-stage renal disease patients.

In order to assess the physical, psychological and social impact of end-stage renal disease (ESRD) 102 patients on maintenance dialysis were assessed on standardized self-report measures, a structured interview schedule, a physician assessment and biochemical data. Patients were assessed on two occasions, 18 months apart. Principal components analysis was used to develop a small number of dimensions to characterize quality of life. Multiple regression analysis of patient variables on initial factor scores (cross-sectional analysis) showed that; hospital dialysis and length of time on dialysis were predictive of more psychological distress; males were less compliant than females; patients on peritoneal dialysis made a poorer adjustment to their illness; and, hospital dialysis was predictive of more social distress. As long term predictors (prospective analysis): initial level of psychological distress predicted long-term level of psychological, social distress and illness adjustment; and initial level of compliance predicted long-term level of compliance.