Literature DB >> 32602724

Asymmetric Synthesis of Axially Chiral Anilides via Organocatalytic Atroposelective N-Acylation.

Dawei Li1, Sijing Wang1, Shulin Ge1, Shunxi Dong1, Xiaoming Feng1.   

Abstract

A highly atroposelective N-acylation reaction of aniline-derived sulfonamides has been developed with chiral isothiourea as the catalyst. This approach provides a facile and efficient route to an array of atropoisomeric sulfonyl substituted anilide products in good yields with high to excellent enantioselectivities.

Entities:  

Year:  2020        PMID： 32602724     DOI： 10.1021/acs.orglett.0c01581

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  6 in total

1.  Atropoenantioselective palladaelectro-catalyzed anilide C-H olefinations viable with natural sunlight as sustainable power source.

Authors:  Johanna Frey; Xiaoyan Hou; Lutz Ackermann
Journal:  Chem Sci       Date:  2022-02-10       Impact factor: 9.825

2.  Solvent directed chemically divergent synthesis of β-lactams and α-amino acid derivatives with chiral isothiourea.

Authors:  Dong-Sheng Ji; Hui Liang; Kai-Xuan Yang; Zhi-Tao Feng; Yong-Chun Luo; Guo-Qiang Xu; Yucheng Gu; Peng-Fei Xu
Journal:  Chem Sci       Date:  2022-01-18       Impact factor: 9.825

Review 3.  Asymmetric Synthesis of Axially Chiral C-N Atropisomers.

Authors:  Patricia Rodríguez-Salamanca; Rosario Fernández; Valentín Hornillos; José M Lassaletta
Journal:  Chemistry       Date:  2022-03-25       Impact factor: 5.020

Review 4.  Construction of Non-Biaryl Atropisomeric Amide Scaffolds Bearing a C-N Axis via Enantioselective Catalysis.

Authors:  Xiao Xiao; Biao Chen; Yi-Ping Yao; Hai-Jie Zhou; Xu Wang; Neng-Zhong Wang; Fen-Er Chen
Journal:  Molecules       Date:  2022-10-04       Impact factor: 4.927

5.  Atroposelective synthesis of N-aryl peptoid atropisomers via a palladium(ii)-catalyzed asymmetric C-H alkynylation strategy.

Authors:  Yong-Jie Wu; Pei-Pei Xie; Gang Zhou; Qi-Jun Yao; Xin Hong; Bing-Feng Shi
Journal:  Chem Sci       Date:  2021-06-09       Impact factor: 9.825

6.  Asymmetric synthesis of N-N axially chiral compounds via organocatalytic atroposelective N-acylation.

Authors:  Wei Lin; Qun Zhao; Yao Li; Ming Pan; Chen Yang; Guo-Hui Yang; Xin Li
Journal:  Chem Sci       Date:  2021-11-24       Impact factor: 9.825
  6 in total

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