Literature DB >> 32601358

A 2020 vision of ocular gene therapy.

Robert E MacLaren1.   

Abstract

Year:  2020        PMID: 32601358     DOI: 10.1038/s41434-020-0170-8

Source DB:  PubMed          Journal:  Gene Ther        ISSN: 0969-7128            Impact factor:   5.250


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  14 in total

1.  Retina transduction by rAAV2 after intravitreal injection: comparison between mouse and rat.

Authors:  Mariana S Dias; Victor G Araujo; Taliane Vasconcelos; Qiuhong Li; William W Hauswirth; Rafael Linden; Hilda Petrs-Silva
Journal:  Gene Ther       Date:  2019-09-27       Impact factor: 5.250

2.  Reduced retinal transduction and enhanced transgene-directed immunogenicity with intravitreal delivery of rAAV following posterior vitrectomy in dogs.

Authors:  R F Boyd; S L Boye; T J Conlon; K E Erger; D G Sledge; I M Langohr; W W Hauswirth; A M Komáromy; S E Boye; S M Petersen-Jones; J T Bartoe
Journal:  Gene Ther       Date:  2016-04-07       Impact factor: 5.250

3.  Factors governing the transduction efficiency of adeno-associated virus in the retinal ganglion cells following intravitreal injection.

Authors:  Xu Cao; Jasmine Yung; Heather Mak; Christopher K S Leung
Journal:  Gene Ther       Date:  2019-01-28       Impact factor: 5.250

4.  Rationally designed AAV2 and AAVrh8R capsids provide improved transduction in the retina and brain.

Authors:  Jennifer A Sullivan; Lisa M Stanek; Michael J Lukason; Jie Bu; Shayla R Osmond; Elizabeth A Barry; Catherine R O'Riordan; Lamya S Shihabuddin; Seng H Cheng; Abraham Scaria
Journal:  Gene Ther       Date:  2018-05-22       Impact factor: 5.250

5.  Serotype survey of AAV gene delivery via subconjunctival injection in mice.

Authors:  Liujiang Song; Telmo Llanga; Laura M Conatser; Violeta Zaric; Brian C Gilger; Matthew L Hirsch
Journal:  Gene Ther       Date:  2018-08-02       Impact factor: 5.250

6.  AAVrh-10 transduces outer retinal cells in rodents and rabbits following intravitreal administration.

Authors:  Yong Zeng; Haohua Qian; Zhijian Wu; Dario Marangoni; Paul A Sieving; Ronald A Bush
Journal:  Gene Ther       Date:  2019-07-15       Impact factor: 5.250

7.  In situ regeneration of retinal pigment epithelium by gene transfer of E2F2: a potential strategy for treatment of macular degenerations.

Authors:  D Kampik; M Basche; U F O Luhmann; K M Nishiguchi; J A E Williams; J Greenwood; S E Moss; H Han; S Azam; Y Duran; S J Robbie; J W B Bainbridge; D F Larkin; A J Smith; R R Ali
Journal:  Gene Ther       Date:  2017-11-30       Impact factor: 5.250

8.  Inducible scAAV2.GRE.MMP1 lowers IOP long-term in a large animal model for steroid-induced glaucoma gene therapy.

Authors:  T Borrás; L K Buie; M G Spiga
Journal:  Gene Ther       Date:  2016-02-08       Impact factor: 5.250

9.  Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina.

Authors:  D G Hickey; T L Edwards; A R Barnard; M S Singh; S R de Silva; M E McClements; J G Flannery; M W Hankins; R E MacLaren
Journal:  Gene Ther       Date:  2017-11-16       Impact factor: 5.250

10.  Development of an optimized AAV2/5 gene therapy vector for Leber congenital amaurosis owing to defects in RPE65.

Authors:  A Georgiadis; Y Duran; J Ribeiro; L Abelleira-Hervas; S J Robbie; B Sünkel-Laing; S Fourali; A Gonzalez-Cordero; E Cristante; M Michaelides; J W B Bainbridge; A J Smith; R R Ali
Journal:  Gene Ther       Date:  2016-09-22       Impact factor: 5.250

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