Literature DB >> 32595823

Acupuncture Therapy in Post-Radiation Head-and-Neck Cancer with Dysgeusia.

Wahyuningsih Djaali1,2, Christina Lanny Simadibrata2, Irma Nareswari2.   

Abstract

Background: Radiation therapy for head-and-neck cancer can cause side-effects, including pain, nausea, vomiting, sensory disorders such as anosmia and dysgeusia, dysphagia, xerostomia, hot flashes, fatigue, sleep disorders, and even anxiety and depression disorders. Therapies using acupuncture are now being adopted at cancer therapy centers. Acupuncture has been clinically proven to reduce the side-effects of cancer therapies, thus, resulting in better quality of life. Case: A 65-year-old man was diagnosed with stage I laryngeal squamous-cell carcinoma (SCC), and had missing taste and pain on swallowing (visual analogue scale [VAS]: 4) after undergoing 30 sessions of radiation therapy for head-and-neck cancer with a total radiation dose of 60 Gy. He received acupuncture at: body points (LI 4 Hegu, LR 3 Taichong, ST 36 Zusanli, SP 6 Sanyinjiao, and ST 40 Fenglong); the Battlefield Acupuncture points of the ear (Cingulate Gyrus, Thalamus, Zero Point, Shen Men, and Omega 2); and on the wrist area (according to a balance method). Acupuncture therapy was given 2 times a week, for 45-minute sessions.
Results: After 12 acupuncture sessions, he had improvement in taste function and pain reduction from VAS 4 to VAS 1. This improvement likely occurred due to acupuncture's anti-inflammatory effects through anti-inflammatory mediator secretion, an antipain effect through ß-endorphin secretion, and nerve-cell regeneration through neurotropic factors' secretion. Conclusions: Routine acupuncture therapy can reduce dysgeusia and pain in postradiated patients with head-and-neck cancer. Acupuncture can be a therapeutic choice for patients with post-radiation head-and-neck cancer toxicity. Copyright 2020, Mary Ann Liebert, Inc., publishers.

Entities:  

Keywords:  acupuncture; dysgeusia; head-and-neck cancer; radiation therapy

Year:  2020        PMID: 32595823      PMCID: PMC7310235          DOI: 10.1089/acu.2020.1410

Source DB:  PubMed          Journal:  Med Acupunct        ISSN: 1933-6586


  14 in total

Review 1.  Mechanisms of Acupuncture Therapy for Cerebral Ischemia: an Evidence-Based Review of Clinical and Animal Studies on Cerebral Ischemia.

Authors:  Wen Zhu; Yang Ye; Yi Liu; Xue-Rui Wang; Guang-Xia Shi; Shuai Zhang; Cun-Zhi Liu
Journal:  J Neuroimmune Pharmacol       Date:  2017-05-19       Impact factor: 4.147

2.  Dysgeusia and health-related quality of life of cancer patients receiving chemotherapy: A cross-sectional study.

Authors:  E Ponticelli; M Clari; S Frigerio; A De Clemente; I Bergese; E Scavino; A Bernardini; C Sacerdote
Journal:  Eur J Cancer Care (Engl)       Date:  2017-01-19       Impact factor: 2.520

3.  Transcutaneous auricular vagus nerve stimulation as a complementary therapy for pediatric epilepsy: a pilot trial.

Authors:  Wei He; Xianghong Jing; Xiaoyu Wang; Peijing Rong; Liang Li; Hong Shi; Hongyan Shang; Yuping Wang; Jianguo Zhang; Bing Zhu
Journal:  Epilepsy Behav       Date:  2013-06-29       Impact factor: 2.937

4.  Pain-relieving effects of acupuncture and electroacupuncture in an animal model of arthritic pain.

Authors:  Jin Hwan Oh; Sun Joon Bai; Zang-Hee Cho; Hee Chul Han; Sun Seek Min; Insop Shim; Hye-Jung Lee; Hyangsook Lee; Bae Hwan Lee
Journal:  Int J Neurosci       Date:  2006-10       Impact factor: 2.292

5.  Relations between brain network activation and analgesic effect induced by low vs. high frequency electrical acupoint stimulation in different subjects: a functional magnetic resonance imaging study.

Authors:  Wei-Ting Zhang; Zhen Jin; Guo-Hong Cui; Kui-Ling Zhang; Lei Zhang; Ya-Wei Zeng; Fei Luo; Andrew C N Chen; Ji-Sheng Han
Journal:  Brain Res       Date:  2003-08-29       Impact factor: 3.252

6.  IL-10 cytokine released from M2 macrophages is crucial for analgesic and anti-inflammatory effects of acupuncture in a model of inflammatory muscle pain.

Authors:  Morgana D da Silva; Franciane Bobinski; Karina L Sato; Sandra J Kolker; Kathleen A Sluka; Adair R S Santos
Journal:  Mol Neurobiol       Date:  2014-06-25       Impact factor: 5.590

Review 7.  Head and Neck Squamous Cell Carcinoma: Update on Epidemiology, Diagnosis, and Treatment.

Authors:  Shanthi Marur; Arlene A Forastiere
Journal:  Mayo Clin Proc       Date:  2016-03       Impact factor: 7.616

Review 8.  Use of acupuncture to alleviate side effects in radiation oncology: Current evidence and future directions.

Authors:  Rebecca Asadpour; Zhiqiang Meng; Kerstin A Kessel; Stephanie E Combs
Journal:  Adv Radiat Oncol       Date:  2016-08-18

9.  Effect of Electroacupuncture in "Zusanli" and "Kunlun" Acupoints on TLR4 Signaling Pathway of Adjuvant Arthritis Rats.

Authors:  Zhe-Qing Dong; Ji Zhu; De-Zhao Lu; Qin Chen; Ying-Ling Xu
Journal:  Am J Ther       Date:  2018 May/Jun       Impact factor: 2.688

Review 10.  Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal disease, and osteoradionecrosis.

Authors:  Herve Y Sroussi; Joel B Epstein; Rene-Jean Bensadoun; Deborah P Saunders; Rajesh V Lalla; Cesar A Migliorati; Natalie Heaivilin; Zachary S Zumsteg
Journal:  Cancer Med       Date:  2017-10-25       Impact factor: 4.452

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  2 in total

Review 1.  Molecular and Neural Mechanism of Dysphagia Due to Cancer.

Authors:  Ikuko Okuni; Yuta Otsubo; Satoru Ebihara
Journal:  Int J Mol Sci       Date:  2021-06-29       Impact factor: 5.923

2.  Acupuncture for radiation-induced toxicity in head and neck squamous cell carcinoma: a systematic review based on PICO criteria.

Authors:  Pierluigi Bonomo; Giulia Stocchi; Saverio Caini; Isacco Desideri; Veronica Santarlasci; Carlotta Becherini; Vittorio Limatola; Luca Giovanni Locatello; Giuditta Mannelli; Giuseppe Spinelli; Carmelo Guido; Lorenzo Livi
Journal:  Eur Arch Otorhinolaryngol       Date:  2021-07-31       Impact factor: 2.503

  2 in total

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