Popliteal Artery Entrapment Syndrome in Siblings.

Popliteal artery entrapment syndrome (PAES) is a rare disease. We treated siblings with this disease. An 18-year-old male consulted our hospital for intermittent claudication of the left lower limb. Contrast-enhanced computed tomography led to a diagnosis of type II PAES. After transection of the medial head of the gastrocnemius muscle, popliteal artery bypass was performed. His younger brother (6 years younger) was also diagnosed with type II PAES, and similar surgery was performed at the age of 19. These cases suggested the involvement of genetic factors in PAES in addition to embryological factors.