Literature DB >> 3259560

Induction of sister chromatid exchanges (SCE) in G0 lymphocytes by plutonium-238 alpha-particles.

S Z Aghamohammadi1, D T Goodhead, J R Savage.   

Abstract

Irradiation of human G0 lymphocytes with plutonium-238 alpha-particles and X-rays was performed to investigate the production of sister chromatid exchanges (SCE). Alpha-particles produce a significant increase in SCE and this elevation is more significant when separated lymphocytes are irradiated. X-ray irradiation did not induce any significant increase in SCE. Therefore the relative biological effectiveness (RBE) for the induction of SCE by alpha-particles in this system is undefined and effectively infinite.

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Year:  1988        PMID: 3259560     DOI: 10.1080/09553008814551271

Source DB:  PubMed          Journal:  Int J Radiat Biol Relat Stud Phys Chem Med        ISSN: 0020-7616


  4 in total

1.  A cytogenetic study of men occupationally exposed to uranium.

Authors:  F Martin; R Earl; E J Tawn
Journal:  Br J Ind Med       Date:  1991-02

Review 2.  Issues in protection from galactic cosmic rays.

Authors:  J W Wilson; S A Thibeault; F A Cucinotta; J L Shinn; M Kim; R Kiefer; F F Badavi
Journal:  Radiat Environ Biophys       Date:  1995-11       Impact factor: 1.925

3.  Space and radiation protection: scientific requirements for space research.

Authors:  W Schimmerling
Journal:  Radiat Environ Biophys       Date:  1995-08       Impact factor: 1.925

4.  A new mechanism for DNA alterations induced by alpha particles such as those emitted by radon and radon progeny.

Authors:  B E Lehnert; E H Goodwin
Journal:  Environ Health Perspect       Date:  1997-09       Impact factor: 9.031

  4 in total

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