| Literature DB >> 32593950 |
A D Snyder1, E Zuniga2, L Ma3, J L Steinberg4, K Woisard5, P A Narayana6, S Lane7, J Schmitz8, F G Moeller9.
Abstract
We sought effective (directional) connectivity parameters associated with response to citalopram in cocaine use disorder (CUD) by conducting a functional magnetic resonance imaging (fMRI) experiment with participants diagnosed with CUD (n = 13) and matched healthy controls (HC; n = 17). CUD participants showed a positive correlation between bilateral DLPFC-to-putamen effective connectivity and treatment effectiveness score. These preliminary results support further investigation of prefrontal-striatal interactions in response to treatment in CUD.Entities:
Keywords: Citalopram; Cocaine use disorder; Effective connectivity; Impulsivity; Selective serotonin reuptake inhibitor; Ssri
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Year: 2020 PMID: 32593950 PMCID: PMC8948471 DOI: 10.1016/j.pscychresns.2020.111127
Source DB: PubMed Journal: Psychiatry Res Neuroimaging ISSN: 0925-4927 Impact factor: 2.376