Sabine Bleiziffer1, Matheus Simonato2, John G Webb3, Josep Rodés-Cabau4, Philippe Pibarot4, Ran Kornowski5, Stephan Windecker6, Magdalena Erlebach7, Alison Duncan8, Moritz Seiffert9, Axel Unbehaun10, Christian Frerker11, Lars Conzelmann12, Harindra Wijeysundera13, Won-Keun Kim14, Matteo Montorfano15, Azeem Latib16, Didier Tchetche17, Abdelhakim Allali18, Mohamed Abdel-Wahab19, Katia Orvin5, Stefan Stortecky6, Henrik Nissen20, Andreas Holzamer21, Marina Urena22, Luca Testa23, Marco Agrifoglio24, Brian Whisenant25, Janarthanan Sathananthan3, Massimo Napodano26, Antonio Landi26, Claudia Fiorina27, Armin Zittermann1, Verena Veulemans28, Jan-Malte Sinning29, Francesco Saia30, Stephen Brecker31, Patrizia Presbitero32, Ole De Backer33, Lars Søndergaard33, Giuseppe Bruschi34, Luis Nombela Franco35, Anna Sonia Petronio36, Marco Barbanti37, Alfredo Cerillo38, Konstantinos Spargias39, Joachim Schofer40, Mauricio Cohen41, Antonio Muñoz-Garcia42, Ariel Finkelstein43, Matti Adam11, Vicenç Serra44, Rui Campante Teles45, Didier Champagnac46, Alessandro Iadanza47, Piotr Chodor48, Holger Eggebrecht49, Robert Welsh50, Adriano Caixeta51, Stefano Salizzoni52, Antonio Dager53, Vincent Auffret54, Asim Cheema55, Timm Ubben56, Marco Ancona15, Tanja Rudolph1, Jan Gummert1, Elaine Tseng57, Stephane Noble58, Matjaz Bunc59, David Roberts60, Malek Kass61, Anuj Gupta62, Martin B Leon63, Danny Dvir64,65. 1. Klinik für Thorax- und Kardiovaskularchirurgie, Herz- und Diabeteszentrum Nordrhein-Westfalen, Georgstraße 11, 32545 Bad Oeynhausen, Germany. 2. Division of Cardiac Surgery, Escola Paulista de Medicina - Universidade Federal de São Paulo, R. Botucatu, 740, São Paulo - SP, 04023-062, Brazil. 3. Centre for Heart Valve Innovation, St. Paul's Hospital, University of British Columbia, 1081 Burrard St, Vancouver, BC V6Z 1Y6, Canada. 4. Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, 1050 Avenue de la Médecine Local 4211 Ferdinand Vandry Pavillon, Québec, QC G1V 0A6, Canada. 5. Department of Cardiology, Rabin Medical Center, Beilinson Hospital in Petach Tikva & Faculty of Medicine at Tel Aviv University, 39 Jabotinski St., Petah Tikva 49100. 6. Universitätsklinik für Kardiologie, Inselspital Bern, Freiburgstrasse 15 3010 Bern, Switzerland. 7. Klinik für Herz- und Gefäßchirurgie, Deutsches Herzzentrum München, Lazarettstraße 36, 80636 München, Germany. 8. Department of Echocardiography, The Royal Brompton Hospital, Sydney Street, London, SW3 6NP, UK. 9. Universitäres Herz- und Gefäßzentrum, Universitätsklinikum Hamburg-Eppendorf, Villa Garbrecht, Martinistraße 52, 20251 Hamburg, Germany. 10. Klinik für Herz-, Thorax- und Gefäßchirurgie, Deutsches Herzzentrum Berlin, Augustenburger Platz 1 13353 Berlin, Germany. 11. Klinik III für Innere Medizin, Uniklinik Köln, Köln, Kerpener Str. 62, 50937 Köln, Germany. 12. Helios Klinik für Herzchirurgie Karlsruhe, Helios Karlsruhe, Franz-Lust-Straße 30, 76185 Karlsruhe, Germany. 13. Schulich Heart Centre, Sunnybrook Health Sciences Centre, 2075 Bayview Ave. Toronto, ON M4N 3M5 Canada. 14. Abteilung für Kardiologie, Kerckhoff-Klinik, Benekestr. 2 - 8, 61231 Bad Nauheim, Germany. 15. Unità Operativa di Cardiologia Interventistica ed Emodinamica, I.R.C.C.S. Ospedale San Raffaele, Via Olgettina n. 60, 20132 Milan, Italy. 16. Division of Cardiology, Montefiore Medical Center, New York, 111 East 210th Street Bronx, NY 10467-2401, USA. 17. Division of Cardiology, Clinique Pasteur, 45 avenue de Lombez BP 27617 31076 Toulouse Cedex 3, France. 18. Klinik für Kardiologie & Angiologie, Segeberger Kliniken, Am Kurpark 1, 23795 Bad Segeberg, Germany. 19. Abteilung für Strukturelle Herzerkrankungen, Universitätsklinikum Leipzig, Strümpellstraße 39 04289 Leipzig, Germany. 20. Department of Cardiology, Odense Universitetshospital, J. B. Winsløws Vej 4, 5000 Odense, Denmark. 21. Herz-, Thorax- und herznahe Gefäßchirurgie, Universitätsklinikum Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, Germany. 22. Department of Cardiology, Hôpital Bichat-Claude-Bernard, 46 Rue Henri Huchard, 75018 Paris, France. 23. Department of Cardiology, I.R.C.C.S. Policlinico San Donato, Piazza Edmondo Malan, 2, 20097 San Donato Milanese, Italy. 24. Sezione di Malattie dell'Apparato Cardiovascolare, Centro Cardiologico Monzino, Via Carlo Parea, 4, 20138 Milan, Italy. 25. Intermountain Heart Institute, Intermountain Healthcare, 5169 Cottonwood St #520, Murray, UT 84107, USA. 26. Dipartimento di Scienze Cardiologiche Toraciche e Vascolari, Università degli Studi di Padova, Via Giustiniani, 2 - 35128 Padova, Italy. 27. Emodinamica, Spedali Civili di Brescia, Piazzale Spedali Civili, 125123 Brescia, Italy. 28. Klinik für Kardiologie, Pneumologie & Angiologie, Universitätsklinikum Düsseldorf, Moorenstraße 5, 40225 Düsseldorf, Germany. 29. Herzzentrum Bonn, Universitätsklinikum Bonn, Sigmund-Freud-Straße 25, 53127 Bonn, Germany. 30. Laboratorio di Emodinamica dell'Istituto di Cardiologia, Università degli Studi di Bologna, Policlinico S.Orsola-Malpighi, Via Giuseppe Massarenti, 9, 40138 Bologna, Italy. 31. Structural Heart Disease Clinic, Department of Cardiology, St. George's University Hospitals, Blackshaw Rd, Tooting, London SW17 0QT, UK. 32. Cardiologia clinica e interventistica, Cardio Center, Humanitas, Via Manzoni 56, 20089 Rozzano, Milano, Italy. 33. Hjertemedicinsk Klinik, Center for Hjerte-, Kar-, Lunge- og Infektionssygdomme, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark. 34. Cardiochirurgia, Ospedale Niguarda Ca' Granda, Piazza Ospedale Maggiore, 3 - 20162 Milan, Italy. 35. Servicio de Cardiología, Hospital Clínico San Carlos, Calle del Prof Martín Lagos, s/n, 28040 Madrid, Spain. 36. Sezione Dipartimentale di Emodinamica, Università di Pisa, Via Roma, 67, 56126 Pisa, Italy. 37. Malattie dell'apparato cardiovascolare, Università degli Studi di Catania, Via Santa Maria del Rosario, 9 (1° piano) 95131 - Catania, Italy. 38. Cardiochirurgia, Azienda Ospedaliero-Universitaria Careggi, Largo Brambilla, 3 - 50134 Firenze, Italy. 39. Transcatheter Heart Valves Department, Hygeia Hospital, Athens, Erithrou Stavrou 4, Marousi 151 23, Greece. 40. Innere Medizin und Kardiologie, Medizinisches Versorgungszentrum, Wördemanns Weg 25-27 22527 Hamburg Germany. 41. The Elaine and Sydney Sussman Cardiac Catheterization Laboratories, Cardiovascular Division, University of Miami Miller School of Medicine, 1400 NW 12th Ave, Miami, FL 33136, USA. 42. Unidad de Hemodinámica, Hospital Universitario Virgen de la Victoria, Campus de Teatinos, S/N, 29010 Málaga, Spain. 43. Division of Cardiology, Tel-Aviv Medical Center, 6 Weizman Street, Tel Aviv 64239, Israel. 44. Servicio de Cardiología, Hospital Vall d'Hebron, Passeig de la Vall d'Hebron, 119, 08035 Barcelona, Spain. 45. Divisão de Cardiologia, Hospital de Santa Cruz, Lisboa, Av. Prof. Dr. Reinaldo dos Santos, 2790-134 Carnaxide, Portugal. 46. Cardiologie Interventionnelle, Cardiologie Tonkin, 158 Rue Léon Blum 69100 Villeurbanne, France. 47. Emodinamica, Azienda Ospedaliera Universitaria Senese, Viale Mario Bracci, 16, 53100 Siena, Italy. 48. Department of Cardiology, Silesian Center for Heart Disease, Marii Skłodowskiej-Curie 9, 41-800 Zabrze, Poland. 49. Interventionelle Kardiologie, Cardioangiologisches Centrum Bethanien, Im Prüfling 23, 60389 Frankfurt am Main, Germany. 50. Mazankowski Alberta Heart Institute, University of Alberta, 11220 83 Ave NW, Edmonton, AB T6G 2B7, Canada. 51. Divisão de Cardiologia, Hospital Israelita Albert Einstein, Av. Albert Einstein, 627/701 - Morumbi, São Paulo - SP, 05653-010, Brazil. 52. Dipartimento Cardiovascolare e Toracico, Città della Salute e della Scienza - "Molinette" Hospital, Corso Bramante, 88, 10126 Torino, Italy. 53. Cardiología, Clinica de Occidente, Cl. 18 Nte. #5-34 Cali, Valle del Cauca, Colombia. 54. Cardiologie et maladies vasculaires, Centre Hospitalier Universitaire de Rennes, 2 Rue Henri le Guilloux, 35000 Rennes, France. 55. Interventional Cardiology, St. Michael's Hospital, 30 Bond St, Toronto, ON M5B 1W8, Canada. 56. Herz-, Gefäß- und Diabeteszentrum, Asklepios Klinik St. Georg, Lohmühlenstraße 5, 20099 Hamburg, Germany. 57. Division of Adult Cardiothoracic Surgery, University of California San Francisco, 4150 Clement St, (112) San Francisco, CA 9412,USA. 58. Unité de cardiologie structurelle, Hôpitaux Universitaires de Genève, Rue Gabrielle-Perret-Gentil 4 1205 Genève, Switzerland. 59. Interventional Cardiology, Ljubljana University Medical Centre, Zaloška cesta 7, 1000 Ljubljana, Slovenia. 60. Division of Cardiology, Blackpool Teaching Hospitals, Whinney Heys Rd, Blackpool FY3 8NR,UK. 61. Section of Cardiology, Department of Internal Medicine, University of Manitoba, 409 Tache Ave, Winnipeg, MB R2H 2A6, Canada. 62. Cardiac Catheterization Laboratory, University of Maryland School of Medicine, 22 S Greene St, Baltimore, MD 21201, USA. 63. Center for Interventional Vascular Therapy, Columbia University Medical Center, 630 W 168th St, New York, NY 10032, USA. 64. Division of Cardiology, University of Washington, 1959 NE Pacific Street, C502-A, PO Box 356422, Seattle, WA 98195, USA. 65. Jesselson Integrated Heart Center, Shaare Zedek Medical Centre, Hebrew University, Shmu'el Bait St 12, Jerusalem, 9103102, Israel.
Abstract
AIMS: Due to bioprosthetic valve degeneration, aortic valve-in-valve (ViV) procedures are increasingly performed. There are no data on long-term outcomes after aortic ViV. Our aim was to perform a large-scale assessment of long-term survival and reintervention after aortic ViV. METHODS AND RESULTS: A total of 1006 aortic ViV procedures performed more than 5 years ago [mean age 77.7 ± 9.7 years; 58.8% male; median STS-PROM score 7.3% (4.2-12.0)] were included in the analysis. Patients were treated with Medtronic self-expandable valves (CoreValve/Evolut, Medtronic Inc., Minneapolis, MN, USA) (n = 523, 52.0%), Edwards balloon-expandable valves (EBEV, SAPIEN/SAPIEN XT/SAPIEN 3, Edwards Lifesciences, Irvine, CA, USA) (n = 435, 43.2%), and other devices (n = 48, 4.8%). Survival was lower at 8 years in patients with small-failed bioprostheses [internal diameter (ID) ≤ 20 mm] compared with those with large-failed bioprostheses (ID > 20 mm) (33.2% vs. 40.5%, P = 0.01). Independent correlates for mortality included smaller-failed bioprosthetic valves [hazard ratio (HR) 1.07 (95% confidence interval (CI) 1.02-1.13)], age [HR 1.21 (95% CI 1.01-1.45)], and non-transfemoral access [HR 1.43 (95% CI 1.11-1.84)]. There were 40 reinterventions after ViV. Independent correlates for all-cause reintervention included pre-existing severe prosthesis-patient mismatch [subhazard ratio (SHR) 4.34 (95% CI 1.31-14.39)], device malposition [SHR 3.75 (95% CI 1.36-10.35)], EBEV [SHR 3.34 (95% CI 1.26-8.85)], and age [SHR 0.59 (95% CI 0.44-0.78)]. CONCLUSIONS: The size of the original failed valve may influence long-term mortality, and the type of the transcatheter valve may influence the need for reintervention after aortic ViV. Published on behalf of the European Society of Cardiology. All rights reserved.
AIMS: Due to bioprosthetic valve degeneration, aortic valve-in-valve (ViV) procedures are increasingly performed. There are no data on long-term outcomes after aortic ViV. Our aim was to perform a large-scale assessment of long-term survival and reintervention after aortic ViV. METHODS AND RESULTS: A total of 1006 aortic ViV procedures performed more than 5 years ago [mean age 77.7 ± 9.7 years; 58.8% male; median STS-PROM score 7.3% (4.2-12.0)] were included in the analysis. Patients were treated with Medtronic self-expandable valves (CoreValve/Evolut, Medtronic Inc., Minneapolis, MN, USA) (n = 523, 52.0%), Edwards balloon-expandable valves (EBEV, SAPIEN/SAPIEN XT/SAPIEN 3, Edwards Lifesciences, Irvine, CA, USA) (n = 435, 43.2%), and other devices (n = 48, 4.8%). Survival was lower at 8 years in patients with small-failed bioprostheses [internal diameter (ID) ≤ 20 mm] compared with those with large-failed bioprostheses (ID > 20 mm) (33.2% vs. 40.5%, P = 0.01). Independent correlates for mortality included smaller-failed bioprosthetic valves [hazard ratio (HR) 1.07 (95% confidence interval (CI) 1.02-1.13)], age [HR 1.21 (95% CI 1.01-1.45)], and non-transfemoral access [HR 1.43 (95% CI 1.11-1.84)]. There were 40 reinterventions after ViV. Independent correlates for all-cause reintervention included pre-existing severe prosthesis-patient mismatch [subhazard ratio (SHR) 4.34 (95% CI 1.31-14.39)], device malposition [SHR 3.75 (95% CI 1.36-10.35)], EBEV [SHR 3.34 (95% CI 1.26-8.85)], and age [SHR 0.59 (95% CI 0.44-0.78)]. CONCLUSIONS: The size of the original failed valve may influence long-term mortality, and the type of the transcatheter valve may influence the need for reintervention after aortic ViV. Published on behalf of the European Society of Cardiology. All rights reserved.
Authors: Victor X Mosquera; Alberto Bouzas-Mosquera; Yago Vilela-González; Carlos Velasco; Jorge Salgado-Fernández; Ramón Calviño-Santos; Nicolás Vázquez-González; José M Vázquez-Rodríguez; José M Herrera-Noreña Journal: Interact Cardiovasc Thorac Surg Date: 2021-07-26
Authors: Pier Pasquale Leone; Fabio Fazzari; Francesco Cannata; Jorge Sanz-Sanchez; Antonio Mangieri; Lorenzo Monti; Ottavia Cozzi; Giulio Giuseppe Stefanini; Renato Bragato; Antonio Colombo; Bernhard Reimers; Damiano Regazzoli Journal: Front Cardiovasc Med Date: 2021-06-04
Authors: Andrea Buono; Diego Maffeo; Giovanni Troise; Francesco Donatelli; Maurizio Tespili; Alfonso Ielasi Journal: J Clin Med Date: 2022-01-11 Impact factor: 4.241