Thanina Fellah1, Jeanne Sibiude2, C Vauloup-Fellous3, A G Cordier4, S Guitton5, L Grangeot-Keros6, A Benachi7, L Mandelbrot2, O Picone8. 1. Service de Gynécologie-Obstétrique, Hôpital Delafontaine Centre Hospitalier de Saint-Denis, 2 rue du Docteur Delafontaine 93200 Saint-Denis, France. 2. Service de Gynécologie-Obstétrique, Hôpital Louis Mourier, Assistance Publique-Hôpitaux de Paris, 178 rue des Renouillers, 92701, Colombes cedex, France; Université de Paris, France; Groupe de Recherche sur les Infections pendant la grossesse (GRIG), France; Inserm IAME-U11337, Paris, France. 3. Service de virologie, Centre national de référence de la Rubéole, AP-HP, hôpital Paul Brousse, Inserm U 1193, Univ Paris-Sud Villejuif, France; Groupe de Recherche sur les Infections pendant la grossesse (GRIG), France. 4. Service de Gynécologie-Obstétrique, Hôpital Bicêtre Université Paris Sud. 94270 Le Kremlin Bicêtre, France INSERME UMR-S1139, Faculté de Pharmacie de Paris, Université de Paris, 75006 Paris, France; Groupe de Recherche sur les Infections pendant la grossesse (GRIG), France. 5. Service de Gynécologie-Obstétrique, Hôpital Paul de Viguier CHU Toulouse, 330 avenue de Grande Bretagne 31300 Toulouse, France. 6. Inserm IAME-U11337, Paris, France; Groupe de Recherche sur les Infections pendant la grossesse (GRIG), France. 7. Service de Gynécologie-Obstétrique, Hôpital Beclère, Université Paris Sud. 94270 Le Kremlin Bicêtre, France; Groupe de Recherche sur les Infections pendant la grossesse (GRIG), France. 8. Service de Gynécologie-Obstétrique, Hôpital Louis Mourier, Assistance Publique-Hôpitaux de Paris, 178 rue des Renouillers, 92701, Colombes cedex, France; Université de Paris, France; Groupe de Recherche sur les Infections pendant la grossesse (GRIG), France; Inserm IAME-U11337, Paris, France. Electronic address: olivier.picone@aphp.fr.
Abstract
BACKGROUND: Cytomegalovirus (CMV) is the most frequent cause of congenital viral infection. Approximately 1 % of newborns are congenitally infected and in up to 10 % of them the consequences are severe. Antenatal and postnatal treatments, although promising, are still under evaluation. Hygiene counseling to prevent CMV infection is important and should be systematic. OBJECTIVE: To evaluate health care providers' awareness of CMV maternal and congenital infection in France. STUDY DESIGN: A questionnaire on CMV infection was sent in 2018 by e-mail to obstetricians, pediatricians, midwives and laboratory physicians, and members of medical or midwifery associations. We evaluated their knowledge concerning CMV epidemiology, transmission, symptoms in adults, newborns and long-term effects (scores from 0 to 30) and compared the results with those of our 2012 published study. RESULTS: Of the 597 respondents who completed the questionnaire, 91 % were unaware of the precise transmission route of CMV, 33 % wrongly thought thatin utero therapy for congenital CMV infection was a current standard of care in France, and less than half were familiar with the HAS (Haute Autorité de Santé) and CNGOF (Collège National des Gynécologues et Obstétriciens Français) recommendations. When respondents' knowledge of CMV was greater, patients were given more hygiene counseling. Between 2011 and 2018, knowledge improved among doctors and midwives concerning the route of transmission, the symptoms in adults, and the long-term effects of CMV infection. CONCLUSIONS: Knowledge is improving among healthcare providers, but gaps remain. To bridge these gaps, health care providers should improve their knowledge about congenital CMV by various means: medical reviews, continuing medical education, meetings, conferences, the Internet. Moreover, greater knowledge will allow for more effective counseling of pregnant women, as recommended by HCSP and CNGOF in France.
BACKGROUND: Cytomegalovirus (CMV) is the most frequent cause of congenital viral infection. Approximately 1 % of newborns are congenitally infected and in up to 10 % of them the consequences are severe. Antenatal and postnatal treatments, although promising, are still under evaluation. Hygiene counseling to prevent CMV infection is important and should be systematic. OBJECTIVE: To evaluate health care providers' awareness of CMV maternal and congenital infection in France. STUDY DESIGN: A questionnaire on CMV infection was sent in 2018 by e-mail to obstetricians, pediatricians, midwives and laboratory physicians, and members of medical or midwifery associations. We evaluated their knowledge concerning CMV epidemiology, transmission, symptoms in adults, newborns and long-term effects (scores from 0 to 30) and compared the results with those of our 2012 published study. RESULTS: Of the 597 respondents who completed the questionnaire, 91 % were unaware of the precise transmission route of CMV, 33 % wrongly thought thatin utero therapy for congenital CMV infection was a current standard of care in France, and less than half were familiar with the HAS (Haute Autorité de Santé) and CNGOF (Collège National des Gynécologues et Obstétriciens Français) recommendations. When respondents' knowledge of CMV was greater, patients were given more hygiene counseling. Between 2011 and 2018, knowledge improved among doctors and midwives concerning the route of transmission, the symptoms in adults, and the long-term effects of CMV infection. CONCLUSIONS: Knowledge is improving among healthcare providers, but gaps remain. To bridge these gaps, health care providers should improve their knowledge about congenital CMV by various means: medical reviews, continuing medical education, meetings, conferences, the Internet. Moreover, greater knowledge will allow for more effective counseling of pregnant women, as recommended by HCSP and CNGOF in France.
Authors: Hayley Smithers-Sheedy; Katherine Swinburn; Emma Waight; Ruth King; Lisa Hui; Cheryl A Jones; Kate Daly; William Rawlinson; Sarah Mcintyre; Annabel Webb; Nadia Badawi; Asha Bowen; Philip N Britton; Pamela Palasanthiran; Anne Lainchbury; Antonia Shand Journal: Aust N Z J Obstet Gynaecol Date: 2022-03-29 Impact factor: 1.884