Samira Hassanzadeh1, Mehdi Varmaghani2, Siamak Zarei-Ghanavati3, Javad Heravian Shandiz4, Abbas Azimi Khorasani4. 1. Optometry, Student Research Committee, Paramedical College, Mashhad University of Medical Sciences , Mashhad, Iran. 2. Pharmacoeconomics, Social Determinants of Health Research Center, Mashhad University of Medical Sciences , Mashhad, Iran. 3. Ophthalmology, Eye Research Center, Mashhad University of Medical Sciences , Mashhad, Iran. 4. Optometry, Refractive Error Research Center, Paramedical College, Mashhad University of Medical Sciences , Mashhad, Iran.
Abstract
PURPOSE: The purpose of this study is to assess the pooled prevalence of meibomian gland dysfunction (MGD) and evaluate its risk factors by gender, age, and ethnicity. METHODS: Articles were searched reporting the prevalence of MGD from PubMed, Scopus, Web of Science, and Embase databases. RESULTS: The estimated pooled prevalence of MGD was 0.358 (95% CI 0.26-0.46; I 2: 99.57%). The prevalence of MGD was 0.358 (95% CI 0.24-0.50) in clinical and 0.359 (95% CI 0.22-0.52) in population-based studies. Men were more prone to MGD than women (OR: 1.24, 95% CI 1.01-1.52, p = 0.034). The rate of MGD was between 21.2% and 29.5% in Africans and Caucasians, to 71.0% in Arabs, and 67.5% in Hispanics. CONCLUSION: MGD is a quite prevalent disorder with an estimated pooled prevalence of 35.8%. Men are more prone to MGD than women. There is a large variation between studies in terms of quality, sample size, age ranges, diagnostic criteria, and ethnicity.
PURPOSE: The purpose of this study is to assess the pooled prevalence of meibomian gland dysfunction (MGD) and evaluate its risk factors by gender, age, and ethnicity. METHODS: Articles were searched reporting the prevalence of MGD from PubMed, Scopus, Web of Science, and Embase databases. RESULTS: The estimated pooled prevalence of MGD was 0.358 (95% CI 0.26-0.46; I 2: 99.57%). The prevalence of MGD was 0.358 (95% CI 0.24-0.50) in clinical and 0.359 (95% CI 0.22-0.52) in population-based studies. Men were more prone to MGD than women (OR: 1.24, 95% CI 1.01-1.52, p = 0.034). The rate of MGD was between 21.2% and 29.5% in Africans and Caucasians, to 71.0% in Arabs, and 67.5% in Hispanics. CONCLUSION: MGD is a quite prevalent disorder with an estimated pooled prevalence of 35.8%. Men are more prone to MGD than women. There is a large variation between studies in terms of quality, sample size, age ranges, diagnostic criteria, and ethnicity.
Authors: Francisco Javier Navarro-Gil; Fernando Huete-Toral; Carmen Olalla Domínguez-Godínez; Gonzalo Carracedo; Almudena Crooke Journal: J Clin Med Date: 2022-06-17 Impact factor: 4.964