Holly Etchegary1, Brenda Wilson2, Proton Rahman3, Charlene Simmonds4, Daryl Pullman5. 1. Faculty of Medicine, Memorial University, St John's, NL, Canada; Craig L. Dobbin Centre for Genetics, Rm 4M210, St John's, NL, A1B 3V6. 2. Professor of Medicine and Associate Dean, Community Health and Humanities, Memorial University, St John's, NL A1B 3V6, Canada. 3. Professor of Medicine (Rheumatology), Memorial University and Rheumatologist, Eastern Regional Health Authority, St John's, NL A1B 3V6, Canada. 4. Manager, Health Research Unit, Faculty of Medicine, Memorial University, St. John's, NL A1B 3V6, Canada. 5. Professor of Medicine (Bioethics), Faculty of Medicine, Memorial University, St. John's, NL A1B 3V6, Canada.
Abstract
Aim: To survey the general public about whole genome sequencing interest, including pharmacogenomic testing, and to identify information important for sequencing decisions. Patients & methods: An online survey of 901 members of the general public in an eastern Canadian province. Results: Interest in whole genome sequencing, including pharmacogenomic testing, was high with few differences among demographic variables. Issues identified as very important to sequencing decisions included familial implications of testing, whether treatment was available for conditions tested and knowing who could access genomic information. Most respondents would value support when interpreting sequencing results. Conclusion: Findings reveal the kind of information and support users of sequencing services would value and could inform the implementation of sequencing into care in ways that accord with public preferences and needs.
Aim: To survey the general public about whole genome sequencing interest, including pharmacogenomic testing, and to identify information important for sequencing decisions. Patients & methods: An online survey of 901 members of the general public in an eastern Canadian province. Results: Interest in whole genome sequencing, including pharmacogenomic testing, was high with few differences among demographic variables. Issues identified as very important to sequencing decisions included familial implications of testing, whether treatment was available for conditions tested and knowing who could access genomic information. Most respondents would value support when interpreting sequencing results. Conclusion: Findings reveal the kind of information and support users of sequencing services would value and could inform the implementation of sequencing into care in ways that accord with public preferences and needs.
Entities:
Keywords:
exome; genome; genomic medicine; pharmacogenomics; public attitudes; public engagement; sequencing; survey
Authors: Mathushan Subasri; David Barrett; Jovana Sibalija; Lisa Bitacola; Richard B Kim Journal: Clin Transl Sci Date: 2021-07-16 Impact factor: 4.689