Literature DB >> 32588614

A 56-year-old man with RT-PCR negative nasopharyngeal swabs with Coronavirus Disease 2019 (COVID-19) Pneumonia.

Anna Dworzańska1, Magdalena Tudrujek-Zdunek1, Jerzy Mosiewicz2, Lech Panasiuk3, Krzysztof Tomasiewicz1.   

Abstract

INTRODUCTION: Diagnostic procedure in Coronavirus Disease 2019 (COVID-19) is based mainly on performing real-time-reverse transcription-polymerase chain-reaction (RT-PCR), which has been accepted as the gold standard method. In some cases, such as mutations of the SARS-CoV-2 genome, variable viral load kinetics or laboratory errors, it can be false-negative. CASE REPORT: The case is presented of a 56-year-old man with respiratory tract symptoms, with twice negative results of real-time-reverse transcription-polymerase chain-reaction of nasopharyngeal swabs and positive chest computed tomography, with typical findings for COVID-19 pneumonia.
CONCLUSIONS: Patients with negative RT-PCR results, but with positive computed tomography findings characteristic for COVID-19, should be treated as well as those infected.

Entities:  

Keywords:  COVID-19; Coronavirus Disease 2019; RT-PCR; chest computed tomography; pneumonia; real-time-reverse transcription-polymerase chain-reaction

Mesh:

Year:  2020        PMID: 32588614     DOI: 10.26444/aaem/123543

Source DB:  PubMed          Journal:  Ann Agric Environ Med        ISSN: 1232-1966            Impact factor:   1.447


  1 in total

1.  Single vs replicate Real-Time PCR SARS-CoV-2 testing: Lessons learned for effective pandemic management.

Authors:  William R Webb; Gauri Thapa; Alice Tirnoveanu; Sabrina Kallu; Charlene Loo Jin Yi; Nirali Shah; Joseph Macari; Sadie Mitchell; Graham J Fagg; Rachael N Jeremiah; Sandiya Theminimulle; Romina Vuono; Athina Mylona
Journal:  PLoS One       Date:  2022-07-14       Impact factor: 3.752

  1 in total

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