Literature DB >> 32587203

Retinal detachment with spontaneous dialysis of the ora serrata in a 13-year-old child with neurofibromatosis type 1: A case report.

Rodrigo Clemente-Tomas1, Noemí Ruíz-Del Río1, Amparo Gargallo-Benedicto1, Francisca García-Ibor1, José M Hervas-Hernándis1, Antonio M Duch-Samper2.   

Abstract

A 13-year-old child diagnosed with neurofibromatosis type 1 who on a routine control presented with rhegmatogenous retinal detachment associated to dialysis of the ora serrata in the left eye (OS). There were no clinical signs or history of contuse ocular trauma. Neurofibromatosis produces alterations in fibroblasts of the cortex of the vitreous base. This results in deficient production of the collagen fibers that anchor the vitreous base to the pars plana and the peripheral neurosensory retina. Thus, suboptimal function of the fibroblasts explains spontaneous avulsion of the vitreous base. Such avulsion in turn is related to dialysis of the ora serrata.

Entities:  

Keywords:  Dialysis of the ora serrata; fibroblasts; neurofibromatosis type 1; rhegmatogenous retinal detachment; vitreous base

Mesh:

Year:  2020        PMID: 32587203      PMCID: PMC7574055          DOI: 10.4103/ijo.IJO_1895_19

Source DB:  PubMed          Journal:  Indian J Ophthalmol        ISSN: 0301-4738            Impact factor:   1.848


  4 in total

1.  The fine structure of the vitreous base of the human eye and pathogenesis of pars planitis.

Authors:  J Gärtner
Journal:  Am J Ophthalmol       Date:  1971-06       Impact factor: 5.258

2.  Spontaneous vitreous base avulsion in a patient with neurofibromatosis.

Authors:  U R Desai
Journal:  Indian J Ophthalmol       Date:  1995-03       Impact factor: 1.848

3.  Short communication: neurofibromatosis fibroblasts: slow growth and abnormal morphology.

Authors:  M Zelkowitz; J Stambouly
Journal:  Pediatr Res       Date:  1981-03       Impact factor: 3.756

4.  Diminished epidermal growth factor binding by neurofibromatosis fibroblasts.

Authors:  M Zelkowitz; J Stambouly
Journal:  Ann Neurol       Date:  1980-09       Impact factor: 10.422

  4 in total
  1 in total

1.  Novel and Unusual Retinal Findings in Two Patients with Neurofibromatosis Type 1.

Authors:  David A Kilgore; Riley Sanders; Sami Uwaydat
Journal:  Case Rep Ophthalmol       Date:  2020-11-09
  1 in total

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