BACKGROUND: Regional information regarding the characteristics of patients with coronavirus disease (COVID)-19 is needed for a better understanding of the pandemic. OBJECTIVE: The objective of the study to describe the clinical features of COVID-19 patients diagnosed in a tertiary-care center in Mexico City and to assess differences according to the treatment setting (ambulatory vs. hospital) and to the need of intensive care (IC). METHODS: We conducted a prospective cohort, including consecutive patients with COVID-19 from February 26, 2020 to April 11, 2020. RESULTS: We identified 309 patients (140 inpatients and 169 outpatients). The median age was 43 years (interquartile range, 33-54), 59.2% men, and 18.6% healthcare workers (12.3% from our center). The median body mass index (BMI) was 29.00 kg/m2 and 39.6% had obesity. Compared to outpatients, inpatients were older, had comorbidities, cough, and dyspnea more frequently. Twenty-nine (20.7%) inpatients required treatment in the IC unit (ICU). History of diabetes (type 1 or 2) and abdominal pain were more common in ICU patients compared to non-ICU patients. ICU patients had higher BMIs, higher respiratory rates, and lower room-air capillary oxygen saturations. ICU patients showed a more severe inflammatory response as assessed by white blood cell count, neutrophil and platelet count, C-reactive protein, ferritin, procalcitonin, and albumin levels. By the end of the study period, 65 inpatients had been discharged because of improvement, 70 continued hospitalized, and five had died. CONCLUSIONS: Patients with comorbidities, either middle-age obese or elderly complaining of fever, cough, or dyspnea, were more likely to be admitted. At admission, patients with diabetes, high BMI, and clinical or laboratory findings consistent with a severe inflammatory state were more likely to require IC. Copyright:
BACKGROUND: Regional information regarding the characteristics of patients with coronavirus disease (COVID)-19 is needed for a better understanding of the pandemic. OBJECTIVE: The objective of the study to describe the clinical features of COVID-19 patients diagnosed in a tertiary-care center in Mexico City and to assess differences according to the treatment setting (ambulatory vs. hospital) and to the need of intensive care (IC). METHODS: We conducted a prospective cohort, including consecutive patients with COVID-19 from February 26, 2020 to April 11, 2020. RESULTS: We identified 309 patients (140 inpatients and 169 outpatients). The median age was 43 years (interquartile range, 33-54), 59.2% men, and 18.6% healthcare workers (12.3% from our center). The median body mass index (BMI) was 29.00 kg/m2 and 39.6% had obesity. Compared to outpatients, inpatients were older, had comorbidities, cough, and dyspnea more frequently. Twenty-nine (20.7%) inpatients required treatment in the IC unit (ICU). History of diabetes (type 1 or 2) and abdominal pain were more common in ICU patients compared to non-ICU patients. ICU patients had higher BMIs, higher respiratory rates, and lower room-air capillary oxygen saturations. ICU patients showed a more severe inflammatory response as assessed by white blood cell count, neutrophil and platelet count, C-reactive protein, ferritin, procalcitonin, and albumin levels. By the end of the study period, 65 inpatients had been discharged because of improvement, 70 continued hospitalized, and five had died. CONCLUSIONS: Patients with comorbidities, either middle-age obese or elderly complaining of fever, cough, or dyspnea, were more likely to be admitted. At admission, patients with diabetes, high BMI, and clinical or laboratory findings consistent with a severe inflammatory state were more likely to require IC. Copyright:
Authors: Fernando Perez Galaz; Karen Moedano Rico; Maria Elena Lopez-Acosta; Issac Raffoul Cohen; Oscar Cervantes Gutierrez; Raul Cuevas Bustos; Felix Alejandro Perez Tristan; Marcos Jafif Cojab Journal: Int J Surg Case Rep Date: 2020-08-31
Authors: Antonio Olivas-Martínez; José Luis Cárdenas-Fragoso; José Víctor Jiménez; Oscar Arturo Lozano-Cruz; Edgar Ortiz-Brizuela; Víctor Hugo Tovar-Méndez; Carla Medrano-Borromeo; Alejandra Martínez-Valenzuela; Carla Marina Román-Montes; Bernardo Martínez-Guerra; María Fernanda González-Lara; Thierry Hernandez-Gilsoul; Alfonso Gulias Herrero; Karla María Tamez-Flores; Eric Ochoa-Hein; Alfredo Ponce-de-León; Arturo Galindo-Fraga; David Kershenobich-Stalnikowitz; José Sifuentes-Osornio Journal: PLoS One Date: 2021-02-03 Impact factor: 3.240
Authors: Oscar Arturo Lozano-Cruz; José Víctor Jiménez; Antonio Olivas-Martinez; Edgar Ortiz-Brizuela; José Luis Cárdenas-Fragoso; Daniel Azamar-Llamas; Sergio Rodríguez-Rodríguez; Jorge Carlos Oseguera-Moguel; Joel Dorantes-García; Clemente Barrón-Magdaleno; Aldo C Cázares-Diazleal; Carla Marina Román-Montes; Karla María Tamez-Torres; Bernardo Alfonso Martínez-Guerra; Alfonso Gulias-Herrero; María Fernanda González-Lara; Alfredo Ponce-de-León-Garduño; David Kershenobich-Stalnikowitz; José Sifuentes-Osornio Journal: Front Pharmacol Date: 2021-06-03 Impact factor: 5.810
Authors: Barry M Popkin; Shufa Du; William D Green; Melinda A Beck; Taghred Algaith; Christopher H Herbst; Reem F Alsukait; Mohammed Alluhidan; Nahar Alazemi; Meera Shekar Journal: Obes Rev Date: 2020-08-26 Impact factor: 10.867