Literature DB >> 32583364

Application of Various Delivery Methods for CRISPR/dCas9.

Zhixi Liu1,2,3, Zhi Liao4, Yan Chen1, Lizhu Han2,3, Qinan Yin2,3, Hongtao Xiao5,6,7.   

Abstract

As gene-editing technology has become more and more popular in the life sciences, CRISPR has brought good news to scientific researchers because of its efficiency, convenience, and wide application. Its wide application has also promoted the development of basic scientific research, agriculture, basic medicine, and clinical treatment. However, how the CRISPR/dCas9 system is effectively delivered to the target organs or cells is still unknown. This paper briefly introduces the CRISPR/dCas9 system and then lists some common delivery methods and their characteristics.

Keywords:  CRISPR; Delivery; dCas9

Mesh：

Substances：

Year:  2020        PMID： 32583364     DOI： 10.1007/s12033-020-00258-8

Source DB:  PubMed          Journal:  Mol Biotechnol        ISSN： 1073-6085            Impact factor:   2.695


  5 in total

1.  CRISPR/dCas9 for hepatic fibrosis therapy: implications and challenges.

Authors:  Nianan Luo; Wenjun Zhong; Jiangbin Li; Jianguo Lu; Rui Dong
Journal:  Mol Biol Rep       Date:  2022-08-12       Impact factor: 2.742

2.  p63 silencing induces epigenetic modulation to enhance human cardiac fibroblast to cardiomyocyte-like differentiation.

Authors:  Jaya Pratap Pinnamaneni; Vivek P Singh; Mary B Kim; Christopher T Ryan; Aarthi Pugazenthi; Deepthi Sanagasetti; Megumi Mathison; Jianchang Yang; Todd K Rosengart
Journal:  Sci Rep       Date:  2022-07-06       Impact factor: 4.996

Review 3.  Nanomaterial-assisted CRISPR gene-engineering - A hallmark for triple-negative breast cancer therapeutics advancement.

Authors:  Jabeen Farheen; Narayan S Hosmane; Ruibo Zhao; Qingwei Zhao; M Zubair Iqbal; Xiangdong Kong
Journal:  Mater Today Bio       Date:  2022-10-04

4.  Overexpression of bmp4, dazl, nanos3 and sycp2 in Hu Sheep Leydig Cells Using CRISPR/dcas9 System Promoted Male Germ Cell Related Gene Expression.

Authors:  Hua Yang; Mingtian Deng; Wenli Lv; Zongyou Wei; Yu Cai; Peiyong Cheng; Feng Wang; Yanli Zhang
Journal:  Biology (Basel)       Date:  2022-02-11

Review 5.  A Review on Transcriptional Responses of Interactions between Insect Vectors and Plant Viruses.

Authors:  Michael A Catto; Habibu Mugerwa; Brendon K Myers; Sudeep Pandey; Bhabesh Dutta; Rajagopalbabu Srinivasan
Journal:  Cells       Date:  2022-02-16       Impact factor: 6.600
  5 in total

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