Literature DB >> 3258320

Vitamin D deficiency and low osteocalcin concentrations in anorexia nervosa.

V A Fonseca1, V D'Souza, S Houlder, M Thomas, A Wakeling, P Dandona.   

Abstract

The calcium, vitamin D, and osteocalcin concentrations were investigated in 17 patients with anorexia nervosa. Serum 25-hydroxyvitamin D (25 OHD) concentrations below normal were observed in 15 (88%); only two patients has serum 1,25 dihydroxycholecalciferol (1,25(OH)2D) concentrations below normal. Serum parathyroid hormone (PTH) concentration was also normal in all except these two patients. Serum osteocalcin concentration was below normal in seven of 14 patients. Although a low concentration of serum 25 OHD is common in patients with anorexia nervosa in the United Kingdom, 1,25(OH)2D concentrations are usually normal. Hypovitaminosis D with secondary hyperparathyroidism is relatively uncommon. The subnormal osteocalcin concentrations observed in these patients probably reflect diminished osteoblastic activity, which may contribute to their osteopenia.

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Year:  1988        PMID： 3258320      PMCID： PMC1141377          DOI： 10.1136/jcp.41.2.195

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  12 in total

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Authors:  V Fonseca; J Agnew; P Dandona
Journal:  Br Med J (Clin Res Ed)       Date:  1985-02-16

3.  Premature loss of bone in chronic anorexia nervosa.

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Journal:  J Clin Endocrinol Metab       Date:  1981-10       Impact factor: 5.958

5.  Uncoupling of bone formation and resorption by combined oestrogen and progestagen therapy in postmenopausal osteoporosis.

Authors:  C Christiansen; B J Riis; L Nilas; P Rødbro; L Deftos
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6.  Clinical evaluation of bone turnover by serum osteocalcin measurements in a hospital setting.

Authors:  D M Slovik; C M Gundberg; R M Neer; J B Lian
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Review 7.  Vitamin D and bone health in the elderly.

Authors:  A M Parfitt; J C Gallagher; R P Heaney; C C Johnston; R Neer; G D Whedon
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8.  A microassay for 1,25-dihydroxyvitamin D not requiring high performance liquid chromatography: application to clinical studies.

Authors:  T A Reinhardt; R L Horst; J W Orf; B W Hollis
Journal:  J Clin Endocrinol Metab       Date:  1984-01       Impact factor: 5.958

9.  Hyperparathyroidism and low serum osteocalcin despite vitamin D replacement in primary biliary cirrhosis.

Authors:  V Fonseca; O Epstein; D S Gill; R K Menon; M Thomas; N McIntyre; P Dandona
Journal:  J Clin Endocrinol Metab       Date:  1987-05       Impact factor: 5.958

10.  Electrolyte disturbances and cardiac failure with hypomagnesaemia in anorexia nervosa.

Authors:  V Fonseca; C W Havard
Journal:  Br Med J (Clin Res Ed)       Date:  1985-12-14
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  8 in total

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2.  Vitamin D supplementation during short-term caloric restriction in healthy overweight/obese older women: Effect on glycemic indices and serum osteocalcin levels.

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3.  Directly measured free 25-hydroxy vitamin D levels show no evidence of vitamin D deficiency in young Swedish women with anorexia nervosa.

Authors:  Martin Carlsson; Lars Brudin; Pär Wanby
Journal:  Eat Weight Disord       Date:  2017-04-28       Impact factor: 4.652

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5.  Lumbar bone mineral density in anorexia nervosa.

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6.  Low prevalence of vitamin D deficiency among adolescents with anorexia nervosa.

Authors:  A L Haagensen; H A Feldman; J Ringelheim; C M Gordon
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7.  Age-related differences in hormonal and nutritional impact on lean anorexia nervosa bone turnover uncoupling.

Authors:  B Galusca; C Bossu; N Germain; M Kadem; D Frere; M H Lafage-Proust; F Lang; B Estour
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8.  Vitamin D and parathyroid hormone and bone mineralisation in adults with cystic fibrosis.

Authors:  R J Stead; S Houlder; J Agnew; M Thomas; M E Hodson; J C Batten; P Dandona
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  8 in total

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