Literature DB >> 32583136

Evaluation of Appetite-Regulating Hormones ın Young Children with Autism Spectrum Disorder.

Çağla Çelikkol Sadıç1,2, Ayhan Bilgiç3, İbrahim Kılınç4, Mehmet Burhan Oflaz5, Tamer Baysal5.   

Abstract

This study aimed to investigate the role of leptin, ghrelin, neuropeptide Y, and nesfatin-1 in young children with autism spectrum disorder (ASD). A total of 44 children with ASD and 44 healthy controls aged 18-60 months were included. Plasma levels of hormones were measured using commercial enzyme-linked immunosorbent assay kits. Plasma leptin and ghrelin levels were significantly higher in the ASD group than in the control group. However, no significant difference for plasma neuropeptide Y and nesfatin-1 levels was detected between the groups. No relation was found between the severity of ASD symptoms, severity of eating problems, and plasma levels of hormones. Leptin and ghrelin may play a potential role in the pathogenesis of ASD.

Entities:  

Keywords:  Autism; Early childhood; Ghrelin; Leptin; Nesfatin-1; Neuropeptide Y

Mesh：

Substances：

Year:  2021        PMID： 32583136     DOI： 10.1007/s10803-020-04579-0

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN： 0162-3257


  60 in total

1.  Variations of plasma leptin and adiponectin levels in autistic patients.

Authors:  Patrizia Blardi; Arianna de Lalla; Linda Ceccatelli; Guerri Vanessa; Alberto Auteri; Joseph Hayek
Journal:  Neurosci Lett       Date:  2010-05-15       Impact factor: 3.046

2.  Spontaneous mucosal lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms: mucosal immune activation and reduced counter regulatory interleukin-10.

Authors:  Paul Ashwood; Andrew Anthony; Franco Torrente; Andrew J Wakefield
Journal:  J Clin Immunol       Date:  2004-11       Impact factor: 8.317

Review 3.  A synaptic trek to autism.

Authors:  Thomas Bourgeron
Journal:  Curr Opin Neurobiol       Date:  2009-06-21       Impact factor: 6.627

4.  Brief report: plasma leptin levels are elevated in autism: association with early onset phenotype?

Authors:  Paul Ashwood; Christina Kwong; Robin Hansen; Irva Hertz-Picciotto; Lisa Croen; Paula Krakowiak; Wynn Walker; Isaac N Pessah; Judy Van de Water
Journal:  J Autism Dev Disord       Date:  2007-03-09

Review 5.  Therapeutic potential of neuropeptide Y (NPY) receptor ligands.

Authors:  Shaun P Brothers; Claes Wahlestedt
Journal:  EMBO Mol Med       Date:  2010-11       Impact factor: 12.137

Review 6.  Role of ghrelin in the pathophysiology of gastrointestinal disease.

Authors:  Cynthia K Cheung; Justin Che-Yuen Wu
Journal:  Gut Liver       Date:  2013-08-14       Impact factor: 4.519

7.  The Effects of Leptin on Breastfeeding Behaviour.

Authors:  Anna M Cannon; Foteini Kakulas; Anna R Hepworth; Ching Tat Lai; Peter E Hartmann; Donna T Geddes
Journal:  Int J Environ Res Public Health       Date:  2015-09-30       Impact factor: 3.390

8.  Appetite-regulating hormones in early life and relationships with type of feeding and body composition in healthy term infants.

Authors:  Laura M Breij; Monique T Mulder; Leonie C van Vark-van der Zee; Anita C S Hokken-Koelega
Journal:  Eur J Nutr       Date:  2016-05-11       Impact factor: 5.614

9.  Ghrelin Protects Human Lens Epithelial Cells against Oxidative Stress-Induced Damage.

Authors:  Jie Bai; Fan Yang; Li Dong; Yi Zheng
Journal:  Oxid Med Cell Longev       Date:  2017-10-10       Impact factor: 6.543

10.  Evaluating the Levels of Nesfatin-1 and Ghrelin Hormones in Patients with Moderate and Severe Major Depressive Disorders.

Authors:  Sermin Algul; Oguz Ozcelik
Journal:  Psychiatry Investig       Date:  2017-12-01       Impact factor: 2.505
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  3 in total

1.  Brief Report: Plasma Leptin and Mealtime Feeding Behaviors Among Children with Autism Spectrum Disorder: A Pilot Study.

Authors:  Lonnie Zwaigenbaum; Andrea M Haqq; Khushmol K Dhaliwal; Hayford M Avedzi; Caroline Richard
Journal:  J Autism Dev Disord       Date:  2022-05-18

2.  C1q/TNF-related protein-1: Potential biomarker for early diagnosis of autism spectrum disorder.

Authors:  Hamed Raeisy; Paria Bayati; Farshid Noorbakhsh; Mitra Hakim Shooshtari; Mehrdad Eftekhar Ardebili; Mehdi Shekarabi; Nazanin Mojtabavi
Journal:  Int J Immunopathol Pharmacol       Date:  2022 Jan-Dec       Impact factor: 3.219

3.  Assessment of autism-relevant behaviors in C57BKS/J leptin receptor deficient mice.

Authors:  Susan M Greene; Yatzil R Sanchez; Nikhita Pathapati; Gianna N Davis; Georgianna G Gould
Journal:  Horm Behav       Date:  2021-01-20       Impact factor: 3.492
  3 in total

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