Benoît Thomas1, Nelly Contet Audonneau2, Marie Machouart3, Anne Debourgogne3. 1. Université de Lorraine, CHRU-Nancy, Laboratoire de Parasitologie Mycologie, F54000 Nancy, France; Laboratoire de Biologie Médicale, Hôpitaux Privés de Metz, 13 rue de la gendarmerie, 57000 Metz, France. Electronic address: benoit.thomas@hp-metz.fr. 2. Université de Lorraine, CHRU-Nancy, Laboratoire de Parasitologie Mycologie, F54000 Nancy, France. 3. Université de Lorraine, CHRU-Nancy, Laboratoire de Parasitologie Mycologie, F54000 Nancy, France; Université de Lorraine, SIMPA, F-54000 Nancy, France.
Abstract
BACKGROUND: Fusarium is an environmental mold that causes deep or superficial mycosis in immunocompromised or immunocompetent patients respectively. METHODS: This epidemiological study evaluated the frequency of Fusarium infections in our university hospital center in France over a decade from 2007 to 2016 and its representativeness in the main clinical infections. RESULTS: A total of 715 Fusarium sp. were isolated from various sampling sites. Fusarium was detected in 0.47% of blood cultures, 31.1% of ophthalmic samples, and 8.48% of nail samples. The frequency of Fusarium infections was stable over this decade. CONCLUSIONS: The main Fusarium species complexes recorded in this study were Fusarium oxysporum species complex and Fusarium solani species complex, indicating the importance of Fusarium as a fungal agent that should be considered in clinical practice. A focus on invasive fusarioses shows that they all occur in hematology patients.
BACKGROUND:Fusarium is an environmental mold that causes deep or superficial mycosis in immunocompromised or immunocompetent patients respectively. METHODS: This epidemiological study evaluated the frequency of Fusariuminfections in our university hospital center in France over a decade from 2007 to 2016 and its representativeness in the main clinical infections. RESULTS: A total of 715 Fusarium sp. were isolated from various sampling sites. Fusarium was detected in 0.47% of blood cultures, 31.1% of ophthalmic samples, and 8.48% of nail samples. The frequency of Fusariuminfections was stable over this decade. CONCLUSIONS: The main Fusarium species complexes recorded in this study were Fusarium oxysporum species complex and Fusarium solani species complex, indicating the importance of Fusarium as a fungal agent that should be considered in clinical practice. A focus on invasive fusarioses shows that they all occur in hematology patients.