Literature DB >> 3258064

Gene transactivation mediated by the TAT gene of human immunodeficiency virus in transgenic mice.

J S Khillan1, K C Deen, S H Yu, R W Sweet, M Rosenberg, H Westphal.   

Abstract

Transgenic mice were generated carrying either the long terminal repeat of Human Immunodeficiency Virus fused to the bacterial chloramphenicol acetyl transferase reporter gene or a control element of the murine alpha A crystallin gene fused to the tat gene of human immunodeficiency virus. By crossing these two strains, progeny were obtained which carried both transgenes. The bacterial reporter gene was specifically transactivated in the eyes of these animals.

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Year:  1988        PMID： 3258064      PMCID： PMC336325          DOI： 10.1093/nar/16.4.1423

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  19 in total

1.  Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product.

Authors:  S Y Kao; A F Calman; P A Luciw; B M Peterlin
Journal:  Nature       Date:  1987 Dec 3-9       Impact factor: 49.962

2.  Location of the trans-activating region on the genome of human T-cell lymphotropic virus type III.

Authors:  J Sodroski; R Patarca; C Rosen; F Wong-Staal; W Haseltine
Journal:  Science       Date:  1985-07-05       Impact factor: 47.728

3.  HTLV-III expression and production involve complex regulation at the levels of splicing and translation of viral RNA.

Authors:  M B Feinberg; R F Jarrett; A Aldovini; R C Gallo; F Wong-Staal
Journal:  Cell       Date:  1986-09-12       Impact factor: 41.582

4.  Trans-acting transcriptional regulation of human T-cell leukemia virus type III long terminal repeat.

Authors:  J Sodroski; C Rosen; F Wong-Staal; S Z Salahuddin; M Popovic; S Arya; R C Gallo; W A Haseltine
Journal:  Science       Date:  1985-01-11       Impact factor: 47.728

5.  Three novel genes of human T-lymphotropic virus type III: immune reactivity of their products with sera from acquired immune deficiency syndrome patients.

Authors:  S K Arya; R C Gallo
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

6.  Trans-activation of human immunodeficiency virus occurs via a bimodal mechanism.

Authors:  B R Cullen
Journal:  Cell       Date:  1986-09-26       Impact factor: 41.582

7.  Lens-specific expression and developmental regulation of the bacterial chloramphenicol acetyltransferase gene driven by the murine alpha A-crystallin promoter in transgenic mice.

Authors:  P A Overbeek; A B Chepelinsky; J S Khillan; J Piatigorsky; H Westphal
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205

8.  Trans-activator gene of human T-lymphotropic virus type III (HTLV-III).

Authors:  S K Arya; C Guo; S F Josephs; F Wong-Staal
Journal:  Science       Date:  1985-07-05       Impact factor: 47.728

9.  Developmental and tissue-specific expression directed by the alpha 2 type I collagen promoter in transgenic mice.

Authors:  J S Khillan; A Schmidt; P A Overbeek; B de Crombrugghe; H Westphal
Journal:  Proc Natl Acad Sci U S A       Date:  1986-02       Impact factor: 11.205

10.  Differential effects of polyadenylation regions on gene expression in mammalian cells.

Authors:  D S Pfarr; L A Rieser; R P Woychik; F M Rottman; M Rosenberg; M E Reff
Journal:  DNA       Date:  1986-04
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  7 in total

1.  Regulation of the mouse alpha A-crystallin gene: isolation of a cDNA encoding a protein that binds to a cis sequence motif shared with the major histocompatibility complex class I gene and other genes.

Authors:  T Nakamura; D M Donovan; K Hamada; C M Sax; B Norman; J R Flanagan; K Ozato; H Westphal; J Piatigorsky
Journal:  Mol Cell Biol       Date:  1990-07       Impact factor: 4.272

2.  UV activation of human immunodeficiency virus gene expression in transgenic mice.

Authors:  J Vogel; M Cepeda; E Tschachler; L A Napolitano; G Jay
Journal:  J Virol       Date:  1992-01       Impact factor: 5.103

3.  Targeted oncogene activation by site-specific recombination in transgenic mice.

Authors:  M Lakso; B Sauer; B Mosinger; E J Lee; R W Manning; S H Yu; K L Mulder; H Westphal
Journal:  Proc Natl Acad Sci U S A       Date:  1992-07-15       Impact factor: 11.205

4.  Multiplex gene regulation: a two-tiered approach to transgene regulation in transgenic mice.

Authors:  G W Byrne; F H Ruddle
Journal:  Proc Natl Acad Sci U S A       Date:  1989-07       Impact factor: 11.205

5.  Binary system for regulating transgene expression in mice: targeting int-2 gene expression with yeast GAL4/UAS control elements.

Authors:  D M Ornitz; R W Moreadith; P Leder
Journal:  Proc Natl Acad Sci U S A       Date:  1991-02-01       Impact factor: 11.205

6.  Spatial and temporal regulation of a lacZ reporter transgene in a binary transgenic mouse system.

Authors:  D P Gardner; G W Byrne; F H Ruddle; C Kappen
Journal:  Transgenic Res       Date:  1996-01       Impact factor: 2.788

7.  Efficient production of human immunodeficiency virus proteins in transgenic mice.

Authors:  P Jolicoeur; A Laperrière; N Beaulieu
Journal:  J Virol       Date:  1992-06       Impact factor: 5.103
  7 in total

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