Literature DB >> 3258048

Detection of human B-lymphotropic virus (human herpesvirus 6) sequences in B cell lymphoma tissues of three patients.

S F Josephs1, A Buchbinder, H Z Streicher, D V Ablashi, S Z Salahuddin, H G Guo, F Wong-Staal, J Cossman, M Raffeld, J Sundeen.   

Abstract

A survey for HBLV (human B-lymphotropic herpesvirus or human herpesvirus 6) sequences by Southern blot analyses was performed on DNA obtained from a variety of pathologically defined tissues, including a number of lymphomas, leukemias, and tissues from other hematologic disorders. Of the over 50 specimens studied, viral sequences were detected in three lymphomas of B cell derivation: an Epstein-Barr virus-positive African Burkitt's lymphoma, a follicular large cell lymphoma (nodular histocytic lymphoma), and two Epstein-Barr virus-negative tumors from a patient with Sjogren's syndrome. These results are the first indication of HBLV sequences associated with B cell tumors in a limited number of cases and raise the possibility that the virus might be involved in the genesis of some B cell tumors.

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Year:  1988        PMID： 3258048

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


  24 in total

Review 1.  Human herpesvirus 6.

Authors:  D K Braun; G Dominguez; P E Pellett
Journal:  Clin Microbiol Rev       Date:  1997-07       Impact factor: 26.132

2.  Evidence of human herpesvirus 6 in Sjögren syndrome and sarcoidosis.

Authors:  A M Fillet; G Raguin; H Agut; S Boisnic; S Agbo-Godeau; C Robert
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1992-06       Impact factor: 3.267

3.  Human herpesvirus 6 and Epstein-Barr virus in Hodgkin's disease: a controlled study by polymerase chain reaction and in situ hybridization.

Authors:  G Valente; P Secchiero; P Lusso; M C Abete; C Jemma; G Reato; S Kerim; R C Gallo; G Palestro
Journal:  Am J Pathol       Date:  1996-11       Impact factor: 4.307

4.  Expression of human herpesvirus-6 antigens in benign and malignant lymphoproliferative diseases.

Authors:  M Luppi; P Barozzi; R Garber; A Maiorana; G Bonacorsi; T Artusi; R Trovato; R Marasca; G Torelli
Journal:  Am J Pathol       Date:  1998-09       Impact factor: 4.307

5.  A repeat sequence, GGGTTA, is shared by DNA of human herpesvirus 6 and Marek's disease virus.

Authors:  M Kishi; H Harada; M Takahashi; A Tanaka; M Hayashi; M Nonoyama; S F Josephs; A Buchbinder; F Schachter; D V Ablashi
Journal:  J Virol       Date:  1988-12       Impact factor: 5.103

Review 6.  Human cytomegalovirus and human herpesvirus 6 genes that transform and transactivate.

Authors:  J Doniger; S Muralidhar; L J Rosenthal
Journal:  Clin Microbiol Rev       Date:  1999-07       Impact factor: 26.132

7.  Identification and characterization of a human herpesvirus 6 gene segment capable of transactivating the human immunodeficiency virus type 1 long terminal repeat in an Sp1 binding site-dependent manner.

Authors:  J Wang; C Jones; M Norcross; E Bohnlein; A Razzaque
Journal:  J Virol       Date:  1994-03       Impact factor: 5.103

8.  Detection of human herpesvirus 6 and human papillomavirus 16 in cervical carcinoma.

Authors:  M Chen; H Wang; C D Woodworth; P Lusso; Z Berneman; D Kingma; G Delgado; J A DiPaolo
Journal:  Am J Pathol       Date:  1994-12       Impact factor: 4.307

9.  Latent human herpesvirus-6 DNA is sparsely distributed in peripheral blood lymphocytes of healthy adults and patients with lymphocytic disorders.

Authors:  T Sandhoff; J P Kleim; K E Schneweis
Journal:  Med Microbiol Immunol       Date:  1991       Impact factor: 3.402

10.  Identification of the human herpesvirus 6 glycoprotein H and putative large tegument protein genes.

Authors:  S F Josephs; D V Ablashi; S Z Salahuddin; L L Jagodzinski; F Wong-Staal; R C Gallo
Journal:  J Virol       Date:  1991-10       Impact factor: 5.103
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