Literature DB >> 3257929

Regression of intracerebral lesions in T prolymphocytic leukaemia treated with intravenous deoxycoformycin.

F Brito-Babapulle1, D Huang, P Lavender, D Galton, D Catovsky.   

Abstract

A case of T-prolymphocytic leukaemia (T-PLL) presenting with deafness and confusion is reported. Computerised tomography (CT) of the head showed several well-defined, rounded, high attenuation areas in the temporal, parietal and occipital regions of the brain substance that were suggestive of metastases. Treatment with weekly intravenous deoxycoformycin produced complete resolution of the CT abnormalities together with haematological evidence of disease regression 6 weeks after treatment was started.

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Year:  1988        PMID: 3257929     DOI: 10.1111/j.1600-0609.1988.tb00819.x

Source DB:  PubMed          Journal:  Eur J Haematol        ISSN: 0902-4441            Impact factor:   2.997


  3 in total

Review 1.  Pentostatin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in lymphoproliferative disorders.

Authors:  R N Brogden; E M Sorkin
Journal:  Drugs       Date:  1993-10       Impact factor: 9.546

2.  A T-cell prolymphocytic leukemia case with central nervous system involvement.

Authors:  Umit Yavuz Malkan; Gursel Gunes; Okan Yayar; Haluk Demiroglu; Aysun Yesilirmak; Aysegul Uner
Journal:  Int J Clin Exp Med       Date:  2015-08-15

3.  Central nervous system involvement of T-cell prolymphocytic leukemia diagnosed with stereotactic brain biopsy: case report.

Authors:  Selçuk Göçmen; Murat Kutlay; Alev Erikçi; Cem Atabey; Ozkan Sayan; Aptullah Haholu
Journal:  Turk J Haematol       Date:  2014-03-05       Impact factor: 1.831

  3 in total

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