Literature DB >> 32578794

Sars-CoV-2: A clinical update - II.

Mateus da Silveira Cespedes1, José Carlos Rosa Pires de Souza2.   

Abstract

INTRODUCTION: A covid-19 pandemic decreed by WHO has raised greater awareness of it. EPIDEMIOLOGY: The infection, reached the mark of 2,000,000 patients in 33 countries and caused the risk of the presence of comorbidities and advanced age. TRANSMISSIBILITY: The transmissibility calculated so far is similar to the H1N1 epidemic, but with lower mortality rates. PHYSIOPATHOLOGY: The SARS-CoV-2 virus, of the Coronaviridae family, has the capacity for cellular invasion through the angiotensin-converting enzyme 2 does not have a lower respiratory epithelium and in the cells of the small intestine mucosa. CLINICAL MANIFESTATIONS: a presentation can be divided into mild (fever, fatigue, cough, myalgia, and sputum) and severe (cyanosis, dyspnoea, tachypnea, chest pain, hypoxemia and need for clinical measurement) and has an estimated estimate of 2%. DIAGNOSIS: allows the detection of viral load in CRP-TR of patients with high clinical suspicion. TREATMENT: based on supportive measures and infection control. In severe cases, the use of medications such as hydroxychloroquine and azithromycin or medication can be promising. Take care to avoid the use of corticosteroids. There are no restrictions on the use of resources and IECAs / BRAs.

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Year:  2020        PMID: 32578794     DOI: 10.1590/1806-9282.66.4.547

Source DB:  PubMed          Journal:  Rev Assoc Med Bras (1992)        ISSN: 0104-4230            Impact factor:   1.209


  2 in total

1.  A Single Session of Virtual Reality Improved Tiredness, Shortness of Breath, Anxiety, Depression and Well-Being in Hospitalized Individuals with COVID-19: A Randomized Clinical Trial.

Authors:  Isabele Moraes Rodrigues; Adriana Gomes Lima; Ana Evelyn Dos Santos; Anne Carolline Almeida Santos; Luciana Silva do Nascimento; Maria Veronica Cavalcanti Lins Serra; Terezinha de Jesus Santos Pereira; Felipe Douglas Silva Barbosa; Valquiria Martins Seixas; Katia Monte-Silva; Kelly Regina Dias da Silva Scipioni; Daniel Marinho Cezar da Cruz; Daniele Piscitelli; Michela Goffredo; Miburge Bolivar Gois-Junior; Aristela de Freitas Zanona
Journal:  J Pers Med       Date:  2022-05-19

2.  A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry.

Authors:  Yunkai Zhu; Fei Feng; Gaowei Hu; Yuyan Wang; Yin Yu; Yuanfei Zhu; Wei Xu; Xia Cai; Zhiping Sun; Wendong Han; Rong Ye; Di Qu; Qiang Ding; Xinxin Huang; Hongjun Chen; Wei Xu; Youhua Xie; Qiliang Cai; Zhenghong Yuan; Rong Zhang
Journal:  Nat Commun       Date:  2021-02-11       Impact factor: 14.919

  2 in total

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