Literature DB >> 3257850

Electric shock does not save snakebitten rats.

N R Howe1, J L Meisenheimer.   

Abstract

A team of missionary doctors from Ecuador recently described striking success in the treatment of venomous snakebites with a series of brief, high-voltage, low-current electric shocks applied to the bit site. We designed a randomized, controlled, blinded test of their methods in laboratory rats. Venom of the fer-de-lance, Bothrops atrox, was injected subcutaneously into rats in a series of increasing doses. Half of each dose group then was shocked with a device used by the Ecuadoran group. Envenomated animals developed hemorrhagic ulcers at the injection sites, the size of which was strongly related to venom dose. Electric shock did not influence the development of morbidity or the eventual ulcer size in sublethally envenomated animals, nor did shocks reduce mortality in lethally envenomated animals. We conclude that shocks are without effect on snakebitten rats, and we discuss implications of our findings for the treatment of snakebitten human beings.

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Year:  1988        PMID: 3257850     DOI: 10.1016/s0196-0644(88)80118-5

Source DB:  PubMed          Journal:  Ann Emerg Med        ISSN: 0196-0644            Impact factor:   5.721


  5 in total

1.  From ETOH to FAB: the medicalization of therapy for pit viper envenomation.

Authors:  C S Kitchens
Journal:  Trans Am Clin Climatol Assoc       Date:  2001

Review 2.  Snake envenomation. Incidence, clinical presentation and management.

Authors:  B K Nelson
Journal:  Med Toxicol Adverse Drug Exp       Date:  1989 Jan-Feb

3.  Unified treatment algorithm for the management of crotaline snakebite in the United States: results of an evidence-informed consensus workshop.

Authors:  Eric J Lavonas; Anne-Michelle Ruha; William Banner; Vikhyat Bebarta; Jeffrey N Bernstein; Sean P Bush; William P Kerns; William H Richardson; Steven A Seifert; David A Tanen; Steve C Curry; Richard C Dart
Journal:  BMC Emerg Med       Date:  2011-02-03

Review 4.  Snakebite: When the Human Touch Becomes a Bad Touch.

Authors:  Bryan G Fry
Journal:  Toxins (Basel)       Date:  2018-04-21       Impact factor: 4.546

Review 5.  First Aid and Pre-Hospital Management of Venomous Snakebites.

Authors:  Jennifer Parker-Cote; William J Meggs
Journal:  Trop Med Infect Dis       Date:  2018-04-24
  5 in total

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