| Literature DB >> 3257731 |
P Bagavandoss1, S L Kunkel, R C Wiggins, P L Keyes.
Abstract
Utilizing immunocytochemistry numerous macrophages were localized in regressing corpora lutea. In contrast, few macrophages were observed in young corpora lutea. Regressing corpora lutea readily produced TNF-a in vitro in response to lipopolysaccharide, whereas young corpora lutea produced significantly less TNF-a. T lymphocytes were identified in young corpora lutea preceding the appearance of macrophages. These observations suggest that cells of the immune system and cytokines could be important participants in physiological regression of the corpus luteum.Entities:
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Year: 1988 PMID: 3257731 DOI: 10.1210/endo-122-3-1185
Source DB: PubMed Journal: Endocrinology ISSN: 0013-7227 Impact factor: 4.736