Literature DB >> 32576474

Kidney Graft Surveillance Biopsy Utilization and Trends: Results From a Survey of High-Volume Transplant Centers.

Darren M Lee1, Michael M Abecassis1, John J Friedewald2, Stanley Rose1, M Roy First3.   

Abstract

An e-mail-based market research survey focused on high-volume US adult transplant centers was developed and implemented to assess surveillance based on United Network for Organ Sharing/Scientific Registry of Transplant Recipients data: 51 to 100 transplants, 101 to 200 transplants, and more than 200 transplants. Eighty-three centers responded to the survey. Respondent centers represented 13,837/21,167 (65%) of the total kidney transplants in 2018. In total, 38/83 (46%) centers reported the use of surveillance biopsies-20 centers in all patients and 18 in select patients. Surveillance biopsies were performed in 37% (7/19) of centers performing 51 to 100 transplants annually, in 44% (15/34) doing 101 to 200 transplants, and in 53% (16/30) of centers doing more than 200 transplants. Of the 20 centers doing surveillance biopsies in all patients, 17/20 (85%) perform more than 100 annual transplants, and 3/20 (15%) perform less than 100 annual transplants. Of the 45 centers not currently doing surveillance biopsies, 13 (29%) used surveillance biopsies in the past; discontinuation was primarily due to patient inconvenience, adverse events, and cost. Using survey percentages, it is estimated that surveillance biopsies are performed in approximately 34% of kidney transplant recipients and that 74% of all surveillance biopsies occur in centers performing more than 100 kidney transplants per year.
Copyright © 2020 Elsevier Inc. All rights reserved.

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Year:  2020        PMID: 32576474     DOI: 10.1016/j.transproceed.2020.04.1816

Source DB:  PubMed          Journal:  Transplant Proc        ISSN: 0041-1345            Impact factor:   1.066


  3 in total

1.  Combining Blood Gene Expression and Cellfree DNA to Diagnose Subclinical Rejection in Kidney Transplant Recipients.

Authors:  Sookhyeon Park; Kexin Guo; Raymond L Heilman; Emilio D Poggio; David J Taber; Christopher L Marsh; Sunil M Kurian; Steve Kleiboeker; Juston Weems; John Holman; Lihui Zhao; Rohita Sinha; Susan Brietigam; Christabel Rebello; Michael M Abecassis; John J Friedewald
Journal:  Clin J Am Soc Nephrol       Date:  2021-10       Impact factor: 10.614

Review 2.  Beyond the Biopsy: Monitoring Immune Status in Kidney Recipients.

Authors:  Roy D Bloom; Joshua J Augustine
Journal:  Clin J Am Soc Nephrol       Date:  2021-08-06       Impact factor: 10.614

3.  Impact of Subclinical Borderline Inflammation on Kidney Transplant Outcomes.

Authors:  Michael E Seifert; Gaurav Agarwal; Miriam Bernard; Ellen Kasik; S Sikandar Raza; Huma Fatima; Robert S Gaston; Vera Hauptfeld-Dolejsek; Bruce A Julian; Clifton E Kew; Vineeta Kumar; Shikha Mehta; Song Ong; Frida Rosenblum; Graham Towns; Roslyn B Mannon
Journal:  Transplant Direct       Date:  2021-01-26
  3 in total

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