Yueming Luo1, Juan Wu2, Jiayan Lu1, Xi Xu3, Wen Long4, Guangjun Yan5, Mengya Tang5, Li Zou6, Dazhi Xu5, Ping Zhuo5, Qin Si7, Xinping Zheng8. 1. The Second Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510000, China. 2. The Fifth Clinical Medical College of Guangzhou University of Chinese Medicine, Guangzhou 510000, China. 3. Second People's Hospital of Longgang District, Shenzhen 518000, China. 4. Chongqing Red Cross Hospital (People's Hospital of Jiangbei District), Chongqing 400020, China. 5. Jingzhou Hospital of Traditional Chinese Medicine, Jingzhou 434000, China. 6. The Third People's Hospital of Jingzhou, Jingzhou 434000, China. 7. Jingzhou Hospital of Traditional Chinese Medicine, Jingzhou 434000, China. 1415961889@qq.com. 8. Jingzhou Hospital of Traditional Chinese Medicine, Jingzhou 434000, China. 281029189@qq.com.
Abstract
BACKGROUND: The application of factor analysis in the study of the clinical symptoms of coronavirus disease 2019 (COVID-19) was investigated, to provide a reference for basic research on COVID-19 and its prevention and control. METHODS: The data of 60 patients with COVID-19 in Jingzhou Hospital of Traditional Chinese Medicine and the Second People's Hospital of Longgang District in Shenzhen were extracted using principal component analysis. Factor analysis was used to investigate the factors related to symptoms of COVID-19. Based on the combination of factors, the clinical types of the factors were defined according to our professional knowledge. Factor loadings were calculated, and pairwise correlation analysis of symptoms was performed. RESULTS: Factor analysis showed that the clinical symptoms of COVID-19 cases could be divided into respiratory-digestive, neurological, cough-wheezing, upper respiratory, and digestive symptoms. Pairwise correlation analysis showed that there were a total of eight pairs of symptoms: fever-palpitation, coughexpectoration, expectoration-wheezing, dry mouth-bitter taste in the mouth, poor appetite-fatigue, fatiguedizziness, diarrhea-palpitation, and dizziness-headache. CONCLUSIONS: The symptoms and syndromes of COVID-19 are complex. Respiratory symptoms dominate, and digestive symptoms are also present. Factor analysis is suitable for studying the characteristics of the clinical symptoms of COVID-19, providing a new idea for the comprehensive analysis of clinical symptoms.
BACKGROUND: The application of factor analysis in the study of the clinical symptoms of coronavirus disease 2019 (COVID-19) was investigated, to provide a reference for basic research on COVID-19 and its prevention and control. METHODS: The data of 60 patients with COVID-19 in Jingzhou Hospital of Traditional Chinese Medicine and the Second People's Hospital of Longgang District in Shenzhen were extracted using principal component analysis. Factor analysis was used to investigate the factors related to symptoms of COVID-19. Based on the combination of factors, the clinical types of the factors were defined according to our professional knowledge. Factor loadings were calculated, and pairwise correlation analysis of symptoms was performed. RESULTS: Factor analysis showed that the clinical symptoms of COVID-19 cases could be divided into respiratory-digestive, neurological, cough-wheezing, upper respiratory, and digestive symptoms. Pairwise correlation analysis showed that there were a total of eight pairs of symptoms: fever-palpitation, coughexpectoration, expectoration-wheezing, dry mouth-bitter taste in the mouth, poor appetite-fatigue, fatiguedizziness, diarrhea-palpitation, and dizziness-headache. CONCLUSIONS: The symptoms and syndromes of COVID-19 are complex. Respiratory symptoms dominate, and digestive symptoms are also present. Factor analysis is suitable for studying the characteristics of the clinical symptoms of COVID-19, providing a new idea for the comprehensive analysis of clinical symptoms.
Authors: Letícia Martins Raposo; Gabriel Ferreira Diaz Abreu; Felipe Borges de Medeiros Cardoso; André Thiago Jonathas Alves; Paulo Tadeu Cardozo Ribeiro Rosa; Flávio Fonseca Nobre Journal: J Infect Public Health Date: 2022-04-28 Impact factor: 7.537
Authors: Doaa A Mekkawy; Sherif Hamdy; Maged Abdel-Naseer; Hatem S Shehata; Ahmed Al Halfawy; Nevin M Shalaby; Ghaydaa A Shehata; Anwar M Ali; Alaa Elmazny; Sandra M Ahmed; Jumana H Ismail; Aml Ibraheim; Hoda M Abdel-Hamid; Rehab Magdy; Younan Kabara Ayoub; Ahmed E Taha; Nahla Merghany; Nourhan M Soliman; Haidy Elshebawy; Samar E S Abdelal; Lobna El-Ghoneimy; Aussan Al-Athwari; Nirmeen A Kishk; Mona A F Nada; Marwa Farghaly; Amr Hassan; Mohamed I Hegazy; Ahmed Abdelalim; Husam S Mourad; Amira Hassouna; Alshimaa S Othman; Tissa Wijeratne Journal: Brain Sci Date: 2022-01-01