Yong Woo Kim1, Jinho Lee2, Jin-Soo Kim3, Ki Ho Park4. 1. Department of Ophthalmology, SeoulNationalUniversityHospital, SeoulNationalUniversityCollege of Medicine, Seoul, Korea. 2. Department of Ophthalmology, SeoulNationalUniversityHospital, SeoulNationalUniversityCollege of Medicine, Seoul, Korea; Department of Ophthalmology, Hallym University Chuncheon Sacred Heart Hospital, Chuncheon, Korea. 3. Department of Ophthalmology, Chungnam National University Sejong Hospital, Sejong, Korea. 4. Department of Ophthalmology, SeoulNationalUniversityHospital, SeoulNationalUniversityCollege of Medicine, Seoul, Korea. Electronic address: kihopark@snu.ac.kr.
Abstract
PURPOSE: To compare the accuracy for glaucomatous defects and diagnostic power for primary open-angle glaucoma (POAG) between swept-source optical coherence tomography (SS-OCT) and spectral-domain optical coherence tomography (SD-OCT) in myopic eyes. DESIGN: Prospective, case-control study METHODS: One hundred and fifty (150) myopic POAG eyes and 100 healthy myopic eyes underwent SD-OCT and SS-OCT in random order, on the same day. The locations of glaucomatous defect on SD-OCT thickness and deviation maps and SS-OCT wide-field thickness (thickness surface) and SuperPixel maps were rated, and the maps' accuracies were compared. The area under receiver operating characteristic (AUROC) of the peripapillary retinal nerve fiber layer (RNFL) and the macular parameters (GCL++: equivalent to ganglion cell-inner plexiform layer [GCIPL] + RNFL; GCL+: equivalent to GCIPL) from each of the devices for myopic POAG were calculated and compared. RESULTS: The wide-field RNFL thickness (thickness surface) map showed the best accuracy for glaucomatous defect in the inferotemporal (96.4%) and superotemporal (92.4%) regions. The RNFL/GCL++/GCL+ wide-field thickness (thickness surface) map showed better accuracy for glaucomatous defect in both the superotemporal and inferotemporal regions compared with the SD-OCT thickness map (all Ps < 0.05). The average GCL++ (87.6%) and GCL+ (87.5%) thicknesses showed significantly greater AUROC for myopic POAG than did GCIPL thickness from SD-OCT (83.8%, all Ps < 0.05). CONCLUSIONS: In myopic eyes, the SS-OCT wide-field map exhibited better accuracy for glaucomatous defect and greater diagnostic power for POAG compared with the SD-OCT outcomes. This result might have been due to SS-OCT's wider scan and measurement area.
PURPOSE: To compare the accuracy for glaucomatous defects and diagnostic power for primary open-angle glaucoma (POAG) between swept-source optical coherence tomography (SS-OCT) and spectral-domain optical coherence tomography (SD-OCT) in myopic eyes. DESIGN: Prospective, case-control study METHODS: One hundred and fifty (150) myopic POAG eyes and 100 healthy myopic eyes underwent SD-OCT and SS-OCT in random order, on the same day. The locations of glaucomatous defect on SD-OCT thickness and deviation maps and SS-OCT wide-field thickness (thickness surface) and SuperPixel maps were rated, and the maps' accuracies were compared. The area under receiver operating characteristic (AUROC) of the peripapillary retinal nerve fiber layer (RNFL) and the macular parameters (GCL++: equivalent to ganglion cell-inner plexiform layer [GCIPL] + RNFL; GCL+: equivalent to GCIPL) from each of the devices for myopic POAG were calculated and compared. RESULTS: The wide-field RNFL thickness (thickness surface) map showed the best accuracy for glaucomatous defect in the inferotemporal (96.4%) and superotemporal (92.4%) regions. The RNFL/GCL++/GCL+ wide-field thickness (thickness surface) map showed better accuracy for glaucomatous defect in both the superotemporal and inferotemporal regions compared with the SD-OCT thickness map (all Ps < 0.05). The average GCL++ (87.6%) and GCL+ (87.5%) thicknesses showed significantly greater AUROC for myopic POAG than did GCIPL thickness from SD-OCT (83.8%, all Ps < 0.05). CONCLUSIONS: In myopic eyes, the SS-OCT wide-field map exhibited better accuracy for glaucomatous defect and greater diagnostic power for POAG compared with the SD-OCT outcomes. This result might have been due to SS-OCT's wider scan and measurement area.
Authors: Alessandro Rabiolo; Federico Fantaguzzi; Giovanni Montesano; Maria Brambati; Riccardo Sacconi; Francesco Gelormini; Giacinto Triolo; Paolo Bettin; Giuseppe Querques; Francesco Bandello Journal: Transl Vis Sci Technol Date: 2022-06-01 Impact factor: 3.048