Emeline Chapelon1,2,3, Caroline Barry1, Tamara Hubert1, Laure Com-Ruelle4, Jeanne Duclos1,2, Lama Mattar5, Bruno Falissard1, Caroline Huas6,7, Nathalie Godart1,8,9. 1. Université Paris-Saclay, Univ. Paris-Sud, UVSQ, CESP, INSERM, Paris, France. 2. Psychiatry Department for Adolescent and Young Adults, Institut Mutualiste Montsouris, Paris, France. 3. Pediatrics Department, Jean Verdier Hospital, avenue du 14 Juillet, Bondy, France. 4. Institute for Research and Information in Health Economics (Institut de Recherche et de Documentation en Economie de la Santé), Paris, France. 5. Nutrition Division, Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, Beirut, Lebanon. 6. Université Paris-Saclay, Univ. Paris-Sud, UVSQ, CESP, INSERM, Paris, France. caroline.huas@fsef.net. 7. Fondation santé des étudiants de France, 8, rue Emile Deutsch de la Meurthe, 75014, Paris, France. caroline.huas@fsef.net. 8. Fondation santé des étudiants de France, 8, rue Emile Deutsch de la Meurthe, 75014, Paris, France. 9. UFR Simone Veil, UVSQ, Montigny le Bretonneux, France.
Abstract
OBJECTIVE: To compare the global health status, frequency of somatic and psychological problems, and alcohol use in adulthood among women hospitalized in adolescence for severe anorexia nervosa (AN), with a matched control sample from the general population. METHOD: Women (n = 86) who had been hospitalized for AN 9.31 ± 1.82 years previously were compared with 258 controls matched for gender, age, and socio-professional category. Data were retrieved from a French survey on health and social insurance coverage, and was mainly collected by self-report, except for the assessment of current eating disorders for those previously hospitalized for AN (assessed with the MINI). RESULTS: The women who had been hospitalized for AN reported significantly poorer current health status compared to controls (OR 2.9, 95% CI 1.5-5.79). According to the MINI, 13 women previously hospitalized with severe AN still presented an eating disorder (ED). Women with past AN reported more frequent acute throat infections (OR 4.9, 95% CI 1.81-13.51), gastralgia (OR 3.6, 95% CI 1.9-6.83), gastro-oesophageal reflux (OR 5.279, 95%CI 2.11-13.22), excess blood cholesterol or triglyceride levels (OR 2.55, 95% CI 1.03-6.33), anxiety (OR 8.7, 95% CI 3.48-21.8) and depression (OR 5.02 (2.8-9.01). These differences remained significant and of the same order of magnitude in sensitivity analyses among subjects with previous AN but without current ED, except for perceived health status and excess cholesterol and triglyceride levels. DISCUSSION: Women who had been hospitalized for severe AN reported more symptoms 10 years after treatment, implies psychological and somatic follow-up in the long term. LEVEL OF EVIDENCE: Level III, case-control analytic study.
OBJECTIVE: To compare the global health status, frequency of somatic and psychological problems, and alcohol use in adulthood among women hospitalized in adolescence for severe anorexia nervosa (AN), with a matched control sample from the general population. METHOD:Women (n = 86) who had been hospitalized for AN 9.31 ± 1.82 years previously were compared with 258 controls matched for gender, age, and socio-professional category. Data were retrieved from a French survey on health and social insurance coverage, and was mainly collected by self-report, except for the assessment of current eating disorders for those previously hospitalized for AN (assessed with the MINI). RESULTS: The women who had been hospitalized for AN reported significantly poorer current health status compared to controls (OR 2.9, 95% CI 1.5-5.79). According to the MINI, 13 women previously hospitalized with severe AN still presented an eating disorder (ED). Women with past AN reported more frequent acute throat infections (OR 4.9, 95% CI 1.81-13.51), gastralgia (OR 3.6, 95% CI 1.9-6.83), gastro-oesophageal reflux (OR 5.279, 95%CI 2.11-13.22), excess blood cholesterol or triglyceride levels (OR 2.55, 95% CI 1.03-6.33), anxiety (OR 8.7, 95% CI 3.48-21.8) and depression (OR 5.02 (2.8-9.01). These differences remained significant and of the same order of magnitude in sensitivity analyses among subjects with previous AN but without current ED, except for perceived health status and excess cholesterol and triglyceride levels. DISCUSSION: Women who had been hospitalized for severe AN reported more symptoms 10 years after treatment, implies psychological and somatic follow-up in the long term. LEVEL OF EVIDENCE: Level III, case-control analytic study.
Entities:
Keywords:
Adolescence; Anorexia nervosa; Global health; Outcome; Somatic and psychological problems
Authors: Peter Vestergaard; Charlotte Emborg; René K Støving; Claus Hagen; Leif Mosekilde; Kim Brixen Journal: Int J Eat Disord Date: 2002-11 Impact factor: 4.861