Literature DB >> 32572248

Tumour metabolites hinder DNA repair.

Lei-Lei Chen, Yue Xiong.   

Abstract

Entities:  

Keywords:  Cancer; Metabolism

Mesh：

Substances：

Year:  2020        PMID： 32572248      PMCID： PMC7576997          DOI： 10.1038/d41586-020-01569-1

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  11 in total

Review 1.  Inhibition of 2-oxoglutarate dependent oxygenases.

Authors:  Nathan R Rose; Michael A McDonough; Oliver N F King; Akane Kawamura; Christopher J Schofield
Journal:  Chem Soc Rev       Date:  2011-03-10       Impact factor: 54.564

2.  The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases.

Authors:  Rasheduzzaman Chowdhury; Kar Kheng Yeoh; Ya-Min Tian; Lars Hillringhaus; Eleanor A Bagg; Nathan R Rose; Ivanhoe K H Leung; Xuan S Li; Esther C Y Woon; Ming Yang; Michael A McDonough; Oliver N King; Ian J Clifton; Robert J Klose; Timothy D W Claridge; Peter J Ratcliffe; Christopher J Schofield; Akane Kawamura
Journal:  EMBO Rep       Date:  2011-04-01       Impact factor: 8.807

Review 3.  Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.

Authors:  A King; M A Selak; E Gottlieb
Journal:  Oncogene       Date:  2006-08-07       Impact factor: 9.867

4.  Benefit from procarbazine, lomustine, and vincristine in oligodendroglial tumors is associated with mutation of IDH.

Authors:  J Gregory Cairncross; Meihua Wang; Robert B Jenkins; Edward G Shaw; Caterina Giannini; David G Brachman; Jan C Buckner; Karen L Fink; Luis Souhami; Normand J Laperriere; Jason T Huse; Minesh P Mehta; Walter J Curran
Journal:  J Clin Oncol       Date:  2014-02-10       Impact factor: 44.544

5.  2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity.

Authors:  Parker L Sulkowski; Christopher D Corso; Nathaniel D Robinson; Susan E Scanlon; Karin R Purshouse; Hanwen Bai; Yanfeng Liu; Ranjini K Sundaram; Denise C Hegan; Nathan R Fons; Gregory A Breuer; Yuanbin Song; Ketu Mishra-Gorur; Henk M De Feyter; Robin A de Graaf; Yulia V Surovtseva; Maureen Kachman; Stephanie Halene; Murat Günel; Peter M Glazer; Ranjit S Bindra
Journal:  Sci Transl Med       Date:  2017-02-01       Impact factor: 19.319

6.  Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases.

Authors:  Wei Xu; Hui Yang; Ying Liu; Ying Yang; Ping Wang; Se-Hee Kim; Shinsuke Ito; Chen Yang; Pu Wang; Meng-Tao Xiao; Li-xia Liu; Wen-qing Jiang; Jing Liu; Jin-ye Zhang; Bin Wang; Stephen Frye; Yi Zhang; Yan-hui Xu; Qun-ying Lei; Kun-Liang Guan; Shi-min Zhao; Yue Xiong
Journal:  Cancer Cell       Date:  2011-01-18       Impact factor: 38.585

7.  Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors.

Authors:  Mengtao Xiao; Hui Yang; Wei Xu; Shenghong Ma; Huaipeng Lin; Honguang Zhu; Lixia Liu; Ying Liu; Chen Yang; Yanhui Xu; Shimin Zhao; Dan Ye; Yue Xiong; Kun-Liang Guan
Journal:  Genes Dev       Date:  2012-06-07       Impact factor: 12.890

8.  Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60.

Authors:  Yingli Sun; Xiaofeng Jiang; Ye Xu; Marina K Ayrapetov; Lisa A Moreau; Johnathan R Whetstine; Brendan D Price
Journal:  Nat Cell Biol       Date:  2009-09-27       Impact factor: 28.824

Review 9.  Metabolism, Activity, and Targeting of D- and L-2-Hydroxyglutarates.

Authors:  Dan Ye; Kun-Liang Guan; Yue Xiong
Journal:  Trends Cancer       Date:  2018-01-05

10.  Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas.

Authors:  Theo A Knijnenburg; Linghua Wang; Michael T Zimmermann; Nyasha Chambwe; Galen F Gao; Andrew D Cherniack; Huihui Fan; Hui Shen; Gregory P Way; Casey S Greene; Yuexin Liu; Rehan Akbani; Bin Feng; Lawrence A Donehower; Chase Miller; Yang Shen; Mostafa Karimi; Haoran Chen; Pora Kim; Peilin Jia; Eve Shinbrot; Shaojun Zhang; Jianfang Liu; Hai Hu; Matthew H Bailey; Christina Yau; Denise Wolf; Zhongming Zhao; John N Weinstein; Lei Li; Li Ding; Gordon B Mills; Peter W Laird; David A Wheeler; Ilya Shmulevich; Raymond J Monnat; Yonghong Xiao; Chen Wang
Journal:  Cell Rep       Date:  2018-04-03       Impact factor: 9.423
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  4 in total

1.  DNA repair genes are associated with tumor tissue differentiation and immune environment in lung adenocarcinoma: a bioinformatics analysis based on big data.

Authors:  Jiayin Li; Jingxu Zhou; Jing Zhang; Zhiwei Xiao; Wenping Wang; Hanrui Chen; Lizhu Lin; Qiuye Yang
Journal:  J Thorac Dis       Date:  2021-07       Impact factor: 3.005

Review 2.  Metabolic reprogramming and epigenetic modifications on the path to cancer.

Authors:  Linchong Sun; Huafeng Zhang; Ping Gao
Journal:  Protein Cell       Date:  2021-05-29       Impact factor: 15.328

Review 3.  Interplay between Cellular Metabolism and the DNA Damage Response in Cancer.

Authors:  Amandine Moretton; Joanna I Loizou
Journal:  Cancers (Basel)       Date:  2020-07-25       Impact factor: 6.639

4.  Aldolase A and Phospholipase D1 Synergistically Resist Alkylating Agents and Radiation in Lung Cancer.

Authors:  Yu-Chan Chang; Peter Mu-Hsin Chang; Chien-Hsiu Li; Ming-Hsien Chan; Yi-Jang Lee; Ming-Huang Chen; Michael Hsiao
Journal:  Front Oncol       Date:  2022-01-21       Impact factor: 6.244
  4 in total

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