Literature DB >> 32571488

Targeted protection of proximal tubular cells by nanoparticle-enhanced delivery of a TLR9-antagonist.

Zoltán H Endre1, Jonathan H Erlich2.   

Abstract

The kidney target site for injury that leads to acute kidney injury (AKI) is the proximal tubule. Nanoparticle-encapsulation enhanced delivery of a selective Toll-like receptor 9 antagonist to mouse proximal tubules and attenuated experimental ischemia-reperfusion injury in a mouse model of AKI.
Copyright © 2020 International Society of Nephrology. All rights reserved.

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Year:  2020        PMID: 32571488     DOI: 10.1016/j.kint.2020.04.024

Source DB:  PubMed          Journal:  Kidney Int        ISSN: 0085-2538            Impact factor:   10.612


  1 in total

Review 1.  Circulating Mitochondrial DNA Stimulates Innate Immune Signaling Pathways to Mediate Acute Kidney Injury.

Authors:  Jiaye Liu; Zhanjun Jia; Wei Gong
Journal:  Front Immunol       Date:  2021-06-24       Impact factor: 7.561

  1 in total

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