| Literature DB >> 32568191 |
Aldelmo Emmanuel Reyes-Pablo1,2, B Berenice Campa-Córdoba1,2, Nabil Itzi Luna-Viramontes1,2, Miguel Ángel Ontiveros-Torres3, Ignacio Villanueva-Fierro4, Marely Bravo-Muñoz1, Bárbara Sáenz-Ibarra5, Oralia Barbosa6, Parménides Guadarrama-Ortíz7, Linda Garcés-Ramírez2, Fidel de la Cruz2, Charles R Harrington8, Sandra Martínez-Robles1, Erik González-Ballesteros1, George Perry9, Mar Pacheco-Herrero10, José Luna-Muñoz1.
Abstract
We recently developed the National Dementia Biobank in México (BioBanco Nacional de Demencias, BND) as a unit for diagnosis, research, and tissue transfer for research purposes. BND is associated with the Facultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de Mexico (UNAM), Mexico. The donation of fluids, brain, and other organs of deceased donors is crucial for understanding the underlying mechanisms of neurodegenerative diseases and for the development of successful treatment. Our laboratory research focuses on 1) analysis of the molecular processing of the proteins involved in those neurodegenerative diseases termed tauopathies and 2) the search for biomarkers for the non-invasive and early diagnosis of Alzheimer's disease.Entities:
Keywords: Alzheimer’s disease; BioBank; amyloid-βzzm321990; brain tissue; neurodegenerative disease; tau protein; tauopathieszzm321990
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Year: 2020 PMID： 32568191 DOI： 10.3233/JAD-191015
Source DB: PubMed Journal: J Alzheimers Dis ISSN： 1387-2877 Impact factor: 4.472