| Literature DB >> 3256323 |
L Szabo1, S Nishimura, W R Farkas.
Abstract
The possibility that the base, queuine, or the queuine family of tRNAs may play a role in oxidative metabolism has been investigated. (i) The enzymatic insertion of queuine into tRNA requires oxygen. This is true for both the mammalian and bacterial enzyme. (ii) (q-) LM cells (murine fibroblast line) grown in culture had 53% less of the manganese-containing superoxide dismutase than (q+) cells. (iii) There was less thiobarbituric-acid-reactive material in queuine-deficient mouse liver and kidney than in (q+) liver and kidney.Entities:
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Year: 1988 PMID： 3256323
Source DB: PubMed Journal: Biofactors ISSN： 0951-6433 Impact factor: 6.113