Literature DB >> 32562842

pH-dependent ileocolonic drug delivery, part II: preclinical evaluation of novel drugs and novel excipients.

Annemarie Broesder1, Anne-Marijke M A C Kosta2, Herman J Woerdenbag1, Duong N Nguyen1, Henderik W Frijlink1, Wouter L J Hinrichs3.   

Abstract

Novel drugs and novel excipients in pH-dependent ileocolonic drug delivery systems have to be tested in animals. Which animal species are suitable and what in vivo methods are used to verify ileocolonic drug delivery?
Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.

Entities:  

Year:  2020        PMID： 32562842     DOI： 10.1016/j.drudis.2020.06.012

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  1 in total

1.  Formulation and In Vitro Evaluation of Pellets Containing Sulfasalazine and Caffeine to Verify Ileo-Colonic Drug Delivery.

Authors:  Annemarie Broesder; Said Y Bircan; Anneko B de Waard; Anko C Eissens; Henderik W Frijlink; Wouter L J Hinrichs
Journal:  Pharmaceutics       Date:  2021-11-23       Impact factor: 6.321
  1 in total

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