| Literature DB >> 32561300 |
Yasmine Alyassin1, Elshaimaa G Sayed2, Prina Mehta1, Ketan Ruparelia1, Muhammad S Arshad1, Manoochehr Rasekh3, Jennifer Shepherd4, Israfil Kucuk5, Philippe B Wilson6, Neenu Singh1, Ming-Wei Chang7, Dimitrios G Fatouros8, Zeeshan Ahmad9.
Abstract
Recently, remarkable efforts have focused on research towards enhancing and delivering efficacious and advanced therapeutic agents. Even though this involves significant challenges, innovative techniques and materials have been explored to overcome these. The advantageous properties of mesoporous silica nanoparticles (MSNs), such as unique morphologies and geometries, makes then favorable for use for various drug delivery targeting purposes, particularly in cancer therapy. As we discuss here, MSNs have been utilized over the past few decades to improve the efficiency of anticancer drugs by enhancing their solubility to render them suitable for application, reducing adverse effects, and improving their anticancer cytotoxic efficiency.Entities:
Year: 2020 PMID: 32561300 DOI: 10.1016/j.drudis.2020.06.006
Source DB: PubMed Journal: Drug Discov Today ISSN: 1359-6446 Impact factor: 7.851