Literature DB >> 32559588

Impact of FilmArray meningitis encephalitis panel on HSV testing and empiric acyclovir use in children beyond the neonatal period.

Kevin Messacar1, James T Gaensbauer2, Meghan Birkholz3, Claire Palmer4, James K Todd2, Kenneth L Tyler4, Samuel R Dominguez2.   

Abstract

Following implementation of the FilmArray meningitis and encephalitis panel, which enables rapid syndromic cerebrospinal fluid testing, HSV testing doubled in children >60 days with suspected central nervous system infection at Children's Hospital Colorado. Acyclovir initiation was unchanged, but duration decreased. Diagnostic and antimicrobial stewardship is needed for MEP optimization.
Copyright © 2020 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Acyclovir; Antimicrobial stewardship; Diagnostic stewardship; Diagnostics; Encephalitis; Herpes; Meningitis; Pediatrics

Mesh:

Substances:

Year:  2020        PMID: 32559588      PMCID: PMC7384938          DOI: 10.1016/j.diagmicrobio.2020.115085

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN: 0732-8893            Impact factor:   2.803


  11 in total

1.  Impact of the implementation of a rapid meningitis/encephalitis multiplex polymerase chain reaction panel on IV acyclovir duration: multicenter, retrospective cohort of adult and pediatric patients.

Authors:  Martha Evans; Kathryn G Merkel; Jenny Harder; Dusten T Rose
Journal:  Diagn Microbiol Infect Dis       Date:  2019-11-06       Impact factor: 2.803

2.  The management of encephalitis: clinical practice guidelines by the Infectious Diseases Society of America.

Authors:  Allan R Tunkel; Carol A Glaser; Karen C Bloch; James J Sejvar; Christina M Marra; Karen L Roos; Barry J Hartman; Sheldon L Kaplan; W Michael Scheld; Richard J Whitley
Journal:  Clin Infect Dis       Date:  2008-08-01       Impact factor: 9.079

3.  Impact of a Rapid Herpes Simplex Virus PCR Assay on Duration of Acyclovir Therapy.

Authors:  Tam T Van; Kanokporn Mongkolrattanothai; Melissa Arevalo; Maryann Lustestica; Jennifer Dien Bard
Journal:  J Clin Microbiol       Date:  2017-03-08       Impact factor: 5.948

4.  Herpes PCR testing and empiric acyclovir use beyond the neonatal period.

Authors:  James T Gaensbauer; Meghan Birkholz; Kari Pfannenstein; James K Todd
Journal:  Pediatrics       Date:  2014-08-11       Impact factor: 7.124

5.  Using Quality Improvement to Implement a Standardized Approach to Neonatal Herpes Simplex Virus.

Authors:  Laura H Brower; Paria M Wilson; Eileen Murtagh Kurowski; David Haslam; Joshua Courter; Neera Goyal; Michelle Durling; Samir S Shah; Amanda Schondelmeyer
Journal:  Pediatrics       Date:  2019-08       Impact factor: 7.124

6.  Cost-Effectiveness Study of Criteria for Screening Cerebrospinal Fluid To Determine the Need for Herpes Simplex Virus PCR Testing.

Authors:  Ronald G Hauser; Sheldon M Campbell; Cynthia A Brandt; Shiyi Wang
Journal:  J Clin Microbiol       Date:  2017-03-15       Impact factor: 5.948

7.  Intravenous acyclovir and renal dysfunction in children: a matched case control study.

Authors:  Suchitra Rao; Mark J Abzug; Phyllis Carosone-Link; Tori Peterson; Jason Child; Georgette Siparksy; Danielle Soranno; Melissa A Cadnapaphornchai; Eric A F Simões
Journal:  J Pediatr       Date:  2015-02-21       Impact factor: 4.406

8.  Factors associated with delay to acyclovir administration in 184 patients with herpes simplex virus encephalitis.

Authors:  J Poissy; M Wolff; A Dewilde; F Rozenberg; F Raschilas; M Blas; H Georges; C Chaffaut; Y Yazdanpanah
Journal:  Clin Microbiol Infect       Date:  2009-04-21       Impact factor: 8.067

9.  Multicenter Evaluation of BioFire FilmArray Meningitis/Encephalitis Panel for Detection of Bacteria, Viruses, and Yeast in Cerebrospinal Fluid Specimens.

Authors:  Amy L Leber; Kathy Everhart; Joan-Miquel Balada-Llasat; Jillian Cullison; Judy Daly; Sarah Holt; Paul Lephart; Hossein Salimnia; Paul C Schreckenberger; Sharon DesJarlais; Sharon L Reed; Kimberle C Chapin; Lindsay LeBlanc; J Kristie Johnson; Nicole L Soliven; Karen C Carroll; Jo-Anne Miller; Jennifer Dien Bard; Javier Mestas; Matthew Bankowski; Tori Enomoto; Andrew C Hemmert; Kevin M Bourzac
Journal:  J Clin Microbiol       Date:  2016-06-22       Impact factor: 5.948

10.  Insights into pediatric herpes simplex encephalitis from a cohort of 21 children from the California Encephalitis Project, 1998-2011.

Authors:  Tu M To; Ariane Soldatos; Heather Sheriff; D Scott Schmid; Natasha Espinosa; Giorgio Cosentino; Christopher P Preas; Carol A Glaser
Journal:  Pediatr Infect Dis J       Date:  2014-12       Impact factor: 2.129

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  1 in total

1.  Impact of Implementing the Cerebrospinal Fluid FilmArray Meningitis/Encephalitis Panel on Duration of Intravenous Acyclovir Treatment.

Authors:  Madison Clague; Carla Kim; Jason Zucker; Daniel A Green; Yifei Sun; Susan Whittier; Kiran T Thakur
Journal:  Open Forum Infect Dis       Date:  2022-07-22       Impact factor: 4.423

  1 in total

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