Literature DB >> 3255918

Can old people on oral anticoagulants be safely managed as out-patients?

M Joglekar1, K Mohanaruban, A J Bayer, M S Pathy.   

Abstract

Of 62 patients (mean age 75, range 65-92 years) referred to an out-patient anticoagulant clinic specifically for those aged 65 years or more, treatment was considered unsafe in only one patient and was discontinued. Minor bleeding which did not require a significant change in management was recorded on 25 (7%) of 381 clinic visits and one major haemorrhage occurred requiring emergency hospital admission. Anticoagulation was maintained within the therapeutic range on 284 (75%) visits. The results confirm that with appropriate out-patient care and supervision, the risks of oral anticoagulant therapy in the elderly need be no greater than in younger patients.

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Year:  1988        PMID: 3255918      PMCID: PMC2429018          DOI: 10.1136/pgmj.64.756.775

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  10 in total

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Authors:  A M Shepherd; D S Hewick; T A Moreland; I H Stevenson
Journal:  Br J Clin Pharmacol       Date:  1977-06       Impact factor: 4.335

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Authors:  K O'Malley; I H Stevenson; C A Ward; A J Wood; J Crooks
Journal:  Br J Clin Pharmacol       Date:  1977-06       Impact factor: 4.335

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Authors:  B M Duxbury
Journal:  Br Med J (Clin Res Ed)       Date:  1982-03-06

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Authors:  J T Eccles
Journal:  Age Ageing       Date:  1975-08       Impact factor: 10.668

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Authors:  A M Errichetti; A Holden; J Ansell
Journal:  Arch Intern Med       Date:  1984-10

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Authors:  P A Routledge; P H Chapman; D M Davies; M D Rawlins
Journal:  Eur J Clin Pharmacol       Date:  1979-06-12       Impact factor: 2.953

7.  An audit of a medical anticoagulant clinic in a District General Hospital.

Authors:  M Shafi; J Mayberry; B Calcraft
Journal:  Postgrad Med J       Date:  1983-08       Impact factor: 2.401

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Authors:  A R Wintzen; H de Jonge; E A Loeliger; G T Bots
Journal:  Ann Neurol       Date:  1984-11       Impact factor: 10.422

9.  Outpatient oral anticoagulation: guidelines for long-term management.

Authors:  F B Davis; C A Sczupak
Journal:  Postgrad Med       Date:  1979-07       Impact factor: 3.840

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Authors:  M Pegg; J Bourne; A D Mackay; W A Lawton; R B Cole
Journal:  J R Coll Physicians Lond       Date:  1985-01
  10 in total
  6 in total

Review 1.  Out-of-hospital coagulation monitoring and management.

Authors:  J E Ansell
Journal:  J Thromb Thrombolysis       Date:  1999-04       Impact factor: 2.300

2.  Anticoagulation Management as a Risk Factor for Adverse Events: Grounds for Improvement.

Authors: 
Journal:  J Thromb Thrombolysis       Date:  1998-01       Impact factor: 2.300

Review 3.  Causes and problems of nonresponse or poor response to drugs.

Authors:  P Salvà Lacombe; J A García Vicente; J Costa Pagès; P Lucio Morselli
Journal:  Drugs       Date:  1996-04       Impact factor: 9.546

4.  Anticoagulant drugs in the elderly.

Authors: 
Journal:  BMJ       Date:  1988-12-10

Review 5.  Adverse drug reactions. An overview of special considerations in the management of the elderly patient.

Authors:  L A Brawn; C M Castleden
Journal:  Drug Saf       Date:  1990 Nov-Dec       Impact factor: 5.606

Review 6.  Safety of treatment with oral anticoagulants in the elderly. A systematic review.

Authors:  B A Hutten; A W Lensing; R A Kraaijenhagen; M H Prins
Journal:  Drugs Aging       Date:  1999-04       Impact factor: 3.923

  6 in total

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