Literature DB >> 32557986

Comparative analysis of botulinum toxin injection after corrective rhinoplasty for deviated nose and alar asymmetry.

Won Lee1, Tae-Hwan Ahn2, Gwahn-Woo Cheon3, Min-Ji Lee1, Eun-Jung Yang4.   

Abstract

BACKGROUND: Deviated noses and asymmetric nostrils can be corrected using corrective rhinoplasty. However, after proper correction, adjacent facial mimetic muscles can cause recurrence of asymmetry because of preoperative habits.
OBJECTIVES: We performed this study to investigate the effects on botulinum toxin on the prevention of recurrence of asymmetry after corrective rhinoplasty.
METHODS: From January 2016 to December 2019, 60 patients underwent corrective rhinoplasty and 30 received botulinum toxin type A injection (Botulax; Hugel Co.) at the depressor septi nasi and levator labii superioris alaeque nasi muscles, bilaterally. Vertical and horizontal deviations were compared preoperatively and postoperatively.
RESULTS: Postoperative vertical deviation was 0.20° ± 0.65° in the botulinum toxin-injected group and 1.20° ± 0.53° in the control group (P < 0.0001). Horizontal deviation was 0.80° ± 0.52° in the botulinum toxin-injected group and 2.18° ± 0.42° in the control group (P < 0.005). Differences between preoperative and postoperative vertical deviations at 6 months were 2.30° ± 0.03° in patients who received botulinum toxin injection and 1.10° ± 0.22° in controls (P < 0.005).
CONCLUSIONS: Botulinum toxin effectively restricted the paranasal muscles without any significant adverse events. We recommend injecting botulinum toxin after corrective rhinoplasty to prevent recurrence of deviation by facial mimetic muscles.
© 2020 Wiley Periodicals, LLC.

Entities:  

Keywords:  botulinum toxin; corrective rhinoplasty; deviated nose

Mesh:

Substances:

Year:  2020        PMID: 32557986     DOI: 10.1111/jocd.13523

Source DB:  PubMed          Journal:  J Cosmet Dermatol        ISSN: 1473-2130            Impact factor:   2.696


  2 in total

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Authors:  Ali Sajjadian; Shawn Moshrefi
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Review 2.  Botulinum Toxin: An Update on Pharmacology and Newer Products in Development.

Authors:  Supriyo Choudhury; Mark R Baker; Suparna Chatterjee; Hrishikesh Kumar
Journal:  Toxins (Basel)       Date:  2021-01-14       Impact factor: 4.546

  2 in total

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